CONTAINMENT DEVICE WITH MULTI-LAYER RESERVOIR CAP STRUCTURE
First Claim
1. A device for the controlled delivery or exposure of reservoir contents comprising:
- a substrate having at least one reservoir, each reservoir having at least one opening;
reservoir contents disposed in the at least one reservoir;
a reservoir cap formed of an electrically conductive material and closing off the opening, to seal the reservoir contents in the at least one reservoir; and
control circuitry and a power source for selectively disintegrating the reservoir cap, thereby opening the reservoir to release or expose the reservoir contents, wherein the reservoir cap comprises multiple metal layers or multiple layers of metal and semiconductor.
2 Assignments
0 Petitions
Accused Products
Abstract
Devices and methods are provided for the controlled release or exposure of reservoir contents. The device includes a substrate, a plurality of reservoirs in the substrate, reservoir contents disposed in the reservoirs, discrete reservoir caps covering each reservoir to seal the reservoir contents in the reservoirs, and control circuitry for selectively disintegrating the reservoir caps to release or expose the reservoir contents in vivo. At least one of the reservoir caps comprises a first electrically conductive layer coated with one or more protective layers. In one embodiment, the control circuitry comprises an electrical input lead and an electrical output lead connected to and directly contacting each of said reservoir caps and a source of electric power for applying an electrical current through each reservoir cap in an amount effective to rupture each of the reservoir caps.
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Citations
29 Claims
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1. A device for the controlled delivery or exposure of reservoir contents comprising:
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a substrate having at least one reservoir, each reservoir having at least one opening; reservoir contents disposed in the at least one reservoir; a reservoir cap formed of an electrically conductive material and closing off the opening, to seal the reservoir contents in the at least one reservoir; and control circuitry and a power source for selectively disintegrating the reservoir cap, thereby opening the reservoir to release or expose the reservoir contents, wherein the reservoir cap comprises multiple metal layers or multiple layers of metal and semiconductor. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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21. An implantable medical device comprising:
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a substrate having a plurality of discrete reservoirs defined therein; a drug or biosensor disposed in each of the reservoirs; a plurality of electrically conductive reservoir caps covering the reservoirs to seal the reservoir contents in the reservoirs; and control circuitry and a power source for selectively disintegrating each of the reservoir caps by electrothermal ablation in vivo, wherein said reservoir caps comprise multiple metal layers or multiple layers of metal and semiconductor. - View Dependent Claims (22, 23, 24, 25, 26, 27, 28, 29)
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Specification