METHODS AND APPARATUS FOR PERCUTANEOUS AORTIC VALVE REPLACEMENT
First Claim
1. A method for percutaneous aortic valve replacement comprising ablating the native aortic valve with a percutaneously introduced ablation means, said ablation means remaining within the aortic annulus and forming the infrastructure to receive and house a replacement tissue valve.
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Accused Products
Abstract
A delivery system and method for percutaneous aortic valve (PAV) replacement and apparatus used therein. A temporary aortic valve comprised of a reversibly expandable occluding means, such as balloons, surrounds a central catheter mechanism. The temporary valve is positioned within the ascending aorta, just above and downstream from the coronary ostia. The occluding means is configured such that, when fully expanded against the aortic wall, gaps are left that promote continuous coronary perfusion during the cardiac cycle. The temporary valve with occluding means substitutes for the function of the native aortic valve during its replacement. The native aortic valve is next dilated, and then ablated through deployment of low profile, elongated, sequentially delivered stents. The ablation stent(s) displace the native valve tissues and remain within the aortic annulus to receive and provide a structure for retaining the PAV. The PAV is delivered, positioned and deployed within the ablation stent(s) at the aortic annulus with precision and relative ease. Ablation of the native aortic valve removes the structural obstacles to precise PAV placement. The temporary aortic valve mediates the hemodynamic forces upon the devices as encountered by the surgeon following native valve ablation. The temporary valve also promotes patient stability through continuous coronary perfusion and a moderated transvalvular pressure gradient and regurgitation. Sequential delivery of low profile PAV components minimize the risk of trauma and injury to vascular tissues. Mathematical considerations for determining the optimum cross-sectional area for the temporary valve blood perfusion gaps are also described.
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Citations
20 Claims
- 1. A method for percutaneous aortic valve replacement comprising ablating the native aortic valve with a percutaneously introduced ablation means, said ablation means remaining within the aortic annulus and forming the infrastructure to receive and house a replacement tissue valve.
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17. A replacement aortic valve used in percutaneous aortic valve replacement procedures comprising
a plurality of low-profile stents sequentially delivered and concentrically deployed within the aortic annulus; - and
a low profile tissue valve with compact frame deployed within and housed by said low-profile stents. - View Dependent Claims (18, 19)
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20. The replacement valve of claim for 17 wherein said low-profile stents and frame of said tissue valve are fabricated from high strength composite materials.
Specification