Biosensor Calibration System

• US 20090030617A1
• Filed: 07/23/2007
• Published: 01/29/2009
• Est. Priority Date: 07/23/2007
• Status: Active Grant

• Current Assignee: Ascensia Diabetes Care Holdings AG (PHC Holdings Corporation)
• Original Assignee: Bayer Healthcare LLC (Bayer AG)
• Inventors: Perry, Joseph E., Schell, Robert D.
• Granted Patent: US 8,206,564 B2
• Time in Patent Office: Days
• US Class Current: 702/19
• CPC Class Codes: G01N 33/48771 Coding of information, e.g. calibration data, lot number

Abstract

A biosensor system determines an analyte concentration using one or more calibrated correlation equations for an optical and/or electrochemical analysis of a biological fluid. The biosensor system may be implemented using a measurement device and a sensor strip. The measurement device senses circuit patterns on an encoding pattern of the sensor strip. The measurement device determines calibration information in response to the circuit patterns, and uses the calibration information to calibrate one or more of the correlation equations. The measurement device uses the calibrated correlation equations to determine the analyte concentration.

Claims

1. A biosensor for determining an analyte concentration in a biological fluid, comprising:

a measurement device having a processor connected to a pattern read device;

a sensor strip having an encoding pattern with at least two circuits;

where the measurement device and sensor strip implement an analyte analysis, where the analyte analysis has at least one correlation equation;

where the pattern read device senses at least two circuit patterns on the encoding pattern;

where the processor determines calibration information responsive to the circuit patterns;

where the processor calibrates at least one correlation equation responsive to the calibration information; and

where the processor determines an analyte concentration responsive to at least one calibrated correlation equation.

2. The biosensor of claim 1, where the pattern read device selectively applies test signals to the encoding pattern.

3. The biosensor of claim 2, where the pattern read device applies test signals to the encoding pattern, and where the pattern read device drives at least one test signal to ground.

4. The biosensor of claim 3, where the pattern read device applies at least one other test signal at a pull-up voltage.

5. The biosensor of claim 3, where the pattern read device comprises a plurality of test circuits, where a first test circuit drives a first test signal to ground during a first step, and where a second test circuit drives a second test signal to ground during a second step.

6. The biosensor of claim 5, where a third test circuit drives a third test signal to ground during a third step.

8. The biosensor of claim 1, where each circuit has at least two contact areas.

9. The biosensor of claim 1, comprising at least one multiple-contact circuit and at least one single-contact circuit.

11. The biosensor of claim 1, where the test signals are current limited.

12. The biosensor of claim 11, where the test signals are less than about 50 μ

A.

13. The biosensor of claim 1, where the pattern read device generates a pattern signal responsive to the circuit patterns.

16. The biosensor of claim 1, comprising an encoding pattern with a first circuit, a second circuit, and at least one isolated circuit, where the first and second circuits each have at least two contact areas, and where the at least one isolated circuit has one contact area.

17. The biosensor of claim 1, comprising an encoding pattern with a single-contact circuit and a multiple-contact circuit.

21. The biosensor of claim 1, where the processor checks for errors in the calibration information.

22. The biosensor of claim 21, where the processor enforces at least one rule regarding a total number of circuits and a total number of isolated circuits.

7. (canceled)

10. (canceled)

14. (canceled)

15. (canceled)

18. (canceled)

19. (canceled)

20. (canceled)

23. A biosensor for determining an analyte concentration in a biological fluid, comprising:

a measurement device having a processor connected to a pattern read device, where the pattern read device has an array of electrical contacts;

a sensor strip having an encoding pattern, where the encoding pattern has at least two circuits, where each circuit has at least one contact area, where the contact areas are in electrical communication with the electrical contacts;

where the measurement device and sensor strip implement an analyte analysis, where the analyte analysis has at least one correlation equation;

where the electrical contacts selectively apply test signals to the contact areas on the encoding pattern;

where the pattern read device senses at least two circuit patterns on the encoding pattern;

where the processor determines calibration information responsive to the circuit patterns;

where the processor calibrates at least one correlation equation responsive to the calibration information; and

where the processor determines an analyte concentration responsive to at least one calibrated correlation equation.

26. The biosensor of claim 23, comprising an encoding pattern with a single-contact circuit and a multiple-contact circuit.

28. The biosensor of claim 23, comprising a pattern read device with a plurality of test circuits, where at least one of the test circuits drives a test signal to ground in response to a control signal from the processor.

41. The biosensor of claim 23, comprising an encoding pattern with a first circuit, a second circuit, and at least one isolated circuit.

46. The biosensor of claim 23, where the processor checks for errors in the calibration information, and where the processor enforces at least one rule regarding a total number of circuits and a total number of isolated circuits.

24. (canceled)

25. (canceled)

27. (canceled)

29-40. -40. (canceled)

42-45. -45. (canceled)

47. (canceled)

48. A method for calibrating an analysis of an analyte in a biological fluid, comprising:

sensing at least two circuit patterns on an encoding pattern;

determining calibration information in response to the circuit patterns;

calibrating at least one correlation equation in response to the calibration information; and

determining an analyte concentration in response to at least one calibrated correlation equation.

49. The method of claim 48, further comprising selectively applying test signals to the encoding pattern.

50. The method of claim 49, further comprising limiting the current of the test signals.

56. The method of claim 50, further comprising:

applying test signals to the encoding pattern; and

driving at least one test signal to ground.

65. The method of claim 48, further comprising checking for errors in the calibration information.

51-55. -55. (canceled)

57-64. -64. (canceled)

66. (canceled)