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Inline-injection microdevice and microfabricated integrated DNA analysis system using same

  • US 20090035770A1
  • Filed: 10/25/2007
  • Published: 02/05/2009
  • Est. Priority Date: 10/25/2006
  • Status: Active Grant
First Claim
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1. A microfabricated structure for inline injection of a sample plug into a separation channel, comprising:

  • a sample channel region for containing an unpurified sample of an analyte;

    a capture channel region containing a capture matrix for forming a concentrated sample plug, wherein said capture matrix has a selective affinity for the analyte; and

    a separation channel region to receive the sample plug and separate the analyte, wherein the capture channel and separation channel regions are contiguous and/or arranged in a line.

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