CONTINUOUS GLUCOSE MONITORING-DIRECTED ADJUSTMENTS IN BASAL INSULIN RATE AND INSULIN BOLUS DOSING FORMULAS
First Claim
1. A method of treating a diabetic patient with an insulin dosage schedule clinically appropriate for that individual patient comprising:
- testing the patient to determine the patient'"'"'s carbohydrate-to-insulin ratio (CIR) and the correction factor (CF) during an evaluation period under conditions of structured daily activity;
applying the CIR and CF to determine a clinically appropriate basal insulin dosage and insulin bolus dosage; and
applying the insulin dosages to the patient for a period of insulin therapy.
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Accused Products
Abstract
A method for individualized management of diabetes in insulin-dependent patients provides a period of evaluation as the patient adheres to a structured pattern of eating, sleeping, and physical activity. Glucose is monitored with a continuous glucose monitoring system, insulin doses are metered, carbohydrate consumption is quantified, and glucose, carbohydrate, and insulin data are collected and analyzed. Insulin dosage is adjusted in three steps: (1) an insulin dosage is estimated from conventional formulas, (2) adjustments are made according to the patient'"'"'s clinical specifics, and (3) further insulin dose adjustments are made according to glucose data obtained during the evaluation period. By the end of the evaluation period, substantially normal glucose values are achieved, and quantitative relationships from data are calculated that are then applied to determine insulin dosages for an ensuing period of therapy. By this method, diabetic patients achieve a near normal glycemic profile, and without significant occurrence of hypoglycemic episodes.
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Citations
20 Claims
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1. A method of treating a diabetic patient with an insulin dosage schedule clinically appropriate for that individual patient comprising:
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testing the patient to determine the patient'"'"'s carbohydrate-to-insulin ratio (CIR) and the correction factor (CF) during an evaluation period under conditions of structured daily activity; applying the CIR and CF to determine a clinically appropriate basal insulin dosage and insulin bolus dosage; and applying the insulin dosages to the patient for a period of insulin therapy. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification