METHOD OF USING AN ANTI-GROWTH MATRIX AS A BARRIER FOR CELL ATTACHMENT AND OSTEO-INDUCTIVE FACTORS
First Claim
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1. A method for repairing an intervertebral disc comprising:
- forming a hole in an annulus fibrosis;
removing damaged annulus fibrosis or nucleus pulposus material from an intervertebral disc space of an intervertebral disc;
inserting an interbody fusion device into the intervertebral disc space; and
closing the hole formed in the annulus fibrosis at least in part by delivering a growth-inhibiting matrix in or about the hole, the growth-inhibiting matrix adapted to prevent tissue or growth agents associated with the implant from migrating into areas outside the intervertebral disc space.
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Abstract
The present invention generally relates to a method of using a matrix as a barrier for unwanted cell attachment and bone formation in unwanted areas of the human body during implant procedures. More specifically, a growth-inhibiting matrix may be used to prevent migration of osteo-inductive agents or bone tissue from an intervertebral disc space through the outer bands of annulus fibrosis that abuts the spinal tissue, canal, and other surrounding areas.
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Citations
38 Claims
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1. A method for repairing an intervertebral disc comprising:
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forming a hole in an annulus fibrosis; removing damaged annulus fibrosis or nucleus pulposus material from an intervertebral disc space of an intervertebral disc; inserting an interbody fusion device into the intervertebral disc space; and closing the hole formed in the annulus fibrosis at least in part by delivering a growth-inhibiting matrix in or about the hole, the growth-inhibiting matrix adapted to prevent tissue or growth agents associated with the implant from migrating into areas outside the intervertebral disc space. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. A kit comprising:
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i. a composition capable of providing a growth-inhibiting matrix; and ii. a delivery device. - View Dependent Claims (19, 20, 21, 22, 23, 24)
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25. A method for preventing unwanted tissue growth associated with an implant or growth agent, the method comprising:
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disposing an implant, an effective amount of a growth agent, or both into a first region in which growth of a selected tissue type is desired; and disposing a matrix between the first region and a second region in which growth of the selected tissue type is not desired, the matrix adapted to prevent the selected tissue type or growth agent from migrating between the first and second regions. - View Dependent Claims (26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38)
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Specification