Injection Device

• US 20090043264A1
• Filed: 04/21/2006
• Published: 02/12/2009
• Est. Priority Date: 04/24/2005
• Status: Abandoned Application

• Current Assignee: Novo Nordisk A/S
• Original Assignee: Novo Nordisk A/S
• Inventors: Hansen, Michael Ejstrup, Linnebjerg, Steven, Glejbol, Kristian, Moller, Claus Schmidt
• Application Number:
  US11/911,871
• Publication Number:
  US 20090043264A1
• Time in Patent Office: Days
• US Class Current: 604/211
• CPC Class Codes: A61M 2005/3152 including gearings to multiply or attenuate the piston displacing force
• CPC Class Codes: A61M 5/31541 Means preventing setting of a dose beyond the amount remaining in the cartridge
• CPC Class Codes: A61M 5/31551 including axial movement of dose setting member
• CPC Class Codes: A61M 5/31556 Accuracy improving means
• CPC Class Codes: A61M 5/31558 using scaling up or down transmissions, e.g. gearbox
• CPC Class Codes: A61M 5/3156 using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
• CPC Class Codes: A61M 5/31561 using freely adjustable volume steps
• CPC Class Codes: A61M 5/31573 Accuracy improving means
• CPC Class Codes: A61M 5/31575 using scaling up or down transmissions, e.g. gearbox
• CPC Class Codes: A61M 5/3158 performed by axially moving actuator operated by user, e.g. an injection button
• CPC Class Codes: A61M 5/31585 performed by axially moving actuator, e.g. an injection button

Abstract

An injection device for injection of set doses of medicine from a cartridge has a nut (13) that is screwed up along a threaded piston rod (4) during a dose setting operation. The nut is screwed along the piston rod by rotating a dose setting member (17. A rotational coupling mechanism includes an axially displaceable coupling member (25) which is rotated as a function of axial displacement. During dose setting, the nut is allowed to rotate relative to the coupling member. During injection, the coupling member is rotationally locked to the nut. This provides a dose setting and injection mechanism wherein the nut member is both rotated during dose setting and during injection.

Claims

1. An injection device comprising:

a. a housing for a dose setting and injecting mechanism, the housing having a proximal end and a distal end,

b. a rotatable dose setting member,

c. an axially displaceable piston rod having a first thread and an additional longitudinally extending track,

d. a central opening in the housing for engaging the additional longitudinally extending track of the piston rod, thus guiding the angular movement of the piston rod during axial translation of the piston rod,

e. a threaded nut engaging the first thread of the piston rod, the nut being rotatably locked to the dose setting member during dose setting,

f. a rotational coupling mechanism having a coupling member which is axially displaceable from a first position to a second position, the rotational coupling mechanism allowing angular movement of the nut relative to the coupling member during dose setting while preventing angular movement between the nut and the coupling member during injection, wherein the coupling member is angularly coupled to the housing so as to be forced to move angularly as a function of axial displacement of the coupling member relative to the housing during at least a part of the axial displacement from said first to said second position.

2. The injection device as defined in claim 1, wherein the dose setting member is axially displaceable as a result of rotation of the dose setting member relative to the housing, and that the coupling member is so coupled to the dose setting member that axial displacement of the dose setting member substantially corresponds to axial displacement of the coupling member.

3. The injection device as defined in claim 1, wherein the coupling member has a thread and is threadedly engaged with a helical thread disposed in the housing, the thread of the housing having a constant pitch.

4. The injection device as defined in claim 1, wherein the coupling member has a protrusion which mates and engages a longitudinally extending track disposed in the housing the longitudinally extending track having a variable pitch along the extension of the track.

5. The injection device as defined in claim 1, wherein the rotational coupling mechanism comprises an incremental feedback mechanism providing incremental clicks during dose setting corresponding to dose volume.

6. The injection device as defined in claim 1, wherein the injection device further comprises an injection button and a gear box assembly coupling axial movement of the injection button with axial movement of the nut.

7. The injection device as defined in claim 6, wherein the gear box assembly provides a gearing causing the nut to move a distance in the distal direction during injection that is less than the distance moved by the injection button.

8. The injection device as defined in claim 1, wherein the additional longitudinally extending track on the piston rod is helically disposed thereby forming a second thread on the piston rod.

9. The injection device as defined in claim 8, wherein the first thread and the longitudinally extending track on the piston rod are oppositely disposed.

10. The injection device as defined in claim 8, wherein the coupling member has a thread and is threadedly engaged with a helical thread disposed in the housing, the thread of the housing having a constant pitch substantially corresponding to the pitch of the additional longitudinally extending track on the piston rod.

11. The injection device as defined in claim 2, wherein the coupling member has a thread and is threadedly engaged with a helical thread disposed in the housing, the thread of the housing having a constant pitch.

12. The injection device as defined in claim 2, wherein the coupling member has a protrusion which mates and engages a longitudinally extending track disposed in the housing the longitudinally extending track having a variable pitch along the extension of the track.

13. The injection device as defined in claim 9, wherein the coupling member has a thread and is threadedly engaged with a helical thread disposed in the housing, the thread of the housing having a constant pitch substantially corresponding to the pitch of the additional longitudinally extending track on the piston rod.

14. The injection device as defined in claim 2, wherein the rotational coupling mechanism comprises an incremental feedback mechanism providing incremental clicks during dose setting corresponding to dose volume.

15. The injection device as defined in claim 3, wherein the rotational coupling mechanism comprises an incremental feedback mechanism providing incremental clicks during dose setting corresponding to dose volume.

16. The injection device as defined in claim 4, wherein the rotational coupling mechanism comprises an incremental feedback mechanism providing incremental clicks during dose setting corresponding to dose volume.

17. The injection device as defined in claim 2, wherein the injection device further comprises an injection button and a gear box assembly coupling axial movement of the injection button with axial movement of the nut.

18. The injection device as defined in claim 3, wherein the injection device further comprises an injection button and a gear box assembly coupling axial movement of the injection button with axial movement of the nut.

19. The injection device as defined in claim 4, wherein the injection device further comprises an injection button and a gear box assembly coupling axial movement of the injection button with axial movement of the nut.

20. The injection device as defined in claim 5, wherein the injection device further comprises an injection button and a gear box assembly coupling axial movement of the injection button with axial movement of the nut.

21. The injection device as defined in claim 6, wherein the injection device further comprises an injection button and a gear box assembly coupling axial movement of the injection button with axial movement of the nut.