Drug Delivery Devices and Related Components, Systems and Methods
First Claim
Patent Images
1. A drug delivery device, comprising:
- an agitator assembly disposed within a mixing chamber defined by a tubular member of the drug delivery device, the agitator assembly being configured to axially reciprocate within the mixing chamber.
1 Assignment
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Accused Products
Abstract
This description relates to drug delivery devices (100), as well as related components, systems and methods.
111 Citations
50 Claims
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1. A drug delivery device, comprising:
an agitator assembly disposed within a mixing chamber defined by a tubular member of the drug delivery device, the agitator assembly being configured to axially reciprocate within the mixing chamber. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26)
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27. A drug delivery system comprising:
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a drug delivery device forming a mixing chamber therein; a manifold releasably attachable to the delivery device, the manifold comprising a first vial configured to contain a first substance and a second vial configured to contain a second substance, the first and second vials being in fluid communication with one another such that when the first vial contains the first substance and the second vial contains the second substance the first and second substances can be combined to form a third substance; and an fluid moving device in fluid communication with the manifold and arranged to combine the first and second substances when activated in a first mode and to deliver the third substance to the mixing chamber of the drug delivery device when activated in a second mode. - View Dependent Claims (28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38)
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39. A method, comprising:
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axially reciprocating an agitator assembly within a mixing chamber of a drug delivery device to mix a plurality of substances within the mixing chamber; and after mixing the plurality of substances, ejecting the plurality of mixed substances from the mixing chamber. - View Dependent Claims (40, 41, 42, 43, 44, 45, 46, 47, 48)
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49. A method for preparing bone cement, the method comprising:
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providing a drug delivery system comprising a manifold and a delivery device configured for releasable attachment to the manifold; reconstituting a bone morphogenetic protein powder to form a bone morphogenetic protein admixture in the manifold; delivering the bone morphogenetic protein admixture from the manifold to the delivery device; mixing the bone morphogenetic protein admixture with a calcium phosphate matrix contained within the delivery device to form a bone cement paste; and ejecting the bone cement paste from the delivery device.
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50. A drug delivery system comprising:
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a manifold configured to contain a bone morphogenetic protein therein; and a delivery device configured to contain a calcium phosphate matrix therein, and configured for releasable attachment to the manifold so that the bone morphogenetic protein can be delivered to the delivery device when the manifold contains the bone morphogenetic protein, the delivery device comprising an agitator assembly configured to mix the calcium phosphate matrix and the bone morphogenetic protein when the delivery device contains the calcium phosphate matrix and the bone morphogenetic protein is delivered to the delivery device; and an aperture defined in a distal end of the delivery device to allow contents to be ejected from the delivery device.
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Specification