DRUG TITRATION UTILIZING AN IMPLANTABLE MEDICAL DEVICE
First Claim
1. A method for titrating a drug to provide a medical therapy to a patient, the method comprising:
- (i) providing an implantable medical device having a controller;
(ii) providing one or more implantable sensors configured to sense physical parameters of the patient and configured to transmit signals to the controller;
(iii) receiving signals from the one or more sensors at the controller;
(iv) processing the received signals to determine at least two cardiopulmonary characteristics of the patient;
(v) determining a composite index based on the at least two cardiopulmonary characteristics; and
(vi) generating a signal based on the composite index.
1 Assignment
0 Petitions
Accused Products
Abstract
A method for titrating a drug to provide a medical therapy to a patient. The method includes the steps of providing an implantable medical device having a controller, providing one or more implantable sensors configured to sense physical parameters of the patient and configured to transmit signals to the controller. The method further includes the step of receiving signals from the one or more sensors at the controller. The method additionally includes processing the received signals to determine at least two cardiopulmonary characteristics of the patient. The method also includes determining a composite index based on the at least two cardiopulmonary characteristics. In addition, the method includes generating a signal based on the composite index. Medical device systems are also disclosed.
-
Citations
32 Claims
-
1. A method for titrating a drug to provide a medical therapy to a patient, the method comprising:
-
(i) providing an implantable medical device having a controller; (ii) providing one or more implantable sensors configured to sense physical parameters of the patient and configured to transmit signals to the controller; (iii) receiving signals from the one or more sensors at the controller; (iv) processing the received signals to determine at least two cardiopulmonary characteristics of the patient; (v) determining a composite index based on the at least two cardiopulmonary characteristics; and (vi) generating a signal based on the composite index. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 23, 24, 25, 26, 27, 28, 29, 30, 31)
-
-
22. A medical device system for use with a drug titration protocol, the medical device system comprising:
-
(i) a controller; (ii) one or more implantable sensors configured to sense physical parameters of the patient and configured to transmit signals to the controller; and (iii) wherein the system is configured to (a) receive signals from the one or more sensors and process the received signals to determine at least two cardiopulmonary characteristics of the patient; (b) determine a composite index based on the at least two cardiopulmonary characteristics; and (c) generate a signal based on the composite index.
-
-
32. A medical device system for use with a drug titration protocol, the medical device system comprising:
-
(i) a controller; (ii) a plurality of implantable sensors configured to sense physical parameters of the patient and configured to transmit signals to the controller, the plurality of implantable sensors including at least; (a) an electrocardiogram sensor that receives cardiac electrical signals; (b) a blood pressure sensor; and (c) an intra-thoracic impedance sensor; and (iii) wherein the controller is configured to (a) receive signals from the plurality of sensors and process the received signals to determine associated physical characteristics of the patient, including determining; (A) heart rate; (B) mean arterial blood pressure; (C) the presence and degree of atrio-ventricular block; (D) pulmonary edema status; (E) the presence and degree of dyspnea; and (F) CSR/AHI burden; (b) assign an index value to each physical characteristic based on its nature or degree; (c) determine a composite index of physical characteristics by combining the individual index values; and (d) generate a signal based on the composite index, where the signal provides an indication of the patient'"'"'s tolerance of a beta-blocker or the effectiveness of a beta-blocker.
-
Specification