Topical anesthetic for rapid local anesthesia and method of applying a topical anesthetic
First Claim
1. A drug delivery system for topical administration of a local anesthetic agent comprising a local anesthetic agent, an alkane diol, a C8-C34 fatty acid or corresponding alcohol or ester having a melting point below 40°
- C., and a volatile component, wherein the local anesthetic agent is present in an amount such that upon topical application to a surface, evaporation of the volatile component occurs such that the remaining solution is near saturation, at saturation, or above saturation with the local anesthetic agent at the temperature of the surface.
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Accused Products
Abstract
The invention relates to a drug delivery system for the topical administration of anesthetic agents. For example, a topical anesthetic for rapid local anesthesia is provided. The topical anesthetic includes an anesthetic, volatile and non-volatile solvents, and an optional thickener. In addition, a method is taught for applying the topical anesthetic to the face of a patient without occlusion. The anesthetic is applied topically to an area for injection such that the dermatological procedure (cosmetic injections) can be performed in fifteen minutes.
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Citations
27 Claims
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1. A drug delivery system for topical administration of a local anesthetic agent comprising a local anesthetic agent, an alkane diol, a C8-C34 fatty acid or corresponding alcohol or ester having a melting point below 40°
- C., and a volatile component, wherein the local anesthetic agent is present in an amount such that upon topical application to a surface, evaporation of the volatile component occurs such that the remaining solution is near saturation, at saturation, or above saturation with the local anesthetic agent at the temperature of the surface.
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27)
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17. A drug delivery system for topical administration of a local anesthetic agent comprising 4% by weight lidocaine, 4% by weight propylene glycol, 4% by weight oleyl alcohol, 3% by weight hydroxypropylcellulose, 17% by weight polydimethysiloxane, and 68% by weight isopropyl alcohol.
Specification