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DIRECTIONAL EXPRESSION-BASED SCIENTIFIC INFORMATION KNOWLEDGE MANAGEMENT

  • US 20090049019A1
  • Filed: 09/19/2008
  • Published: 02/19/2009
  • Est. Priority Date: 12/16/2005
  • Status: Active Grant
First Claim
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1. A method of integrating expression-based data into a knowledge base comprising at least one pre-existing bi-directional feature set, each bi-directional feature set comprising a list of features and, for at least some of the listed features, up or down expression information relative to a control, the method comprising:

  • receiving a bi-directional input feature set comprising a list of features and, for at least some of the listed features, up or down regulation expression information relative to a control; and

    automatically correlating the input feature set with a plurality or all other pre-existing bi-directional feature sets;

    wherein automatically correlating the input feature set with a bi-directional pre-existing feature set comprises determining multiple individual correlation scores and, from the multiple individual correlation scores, determining an overall correlation score and a correlation direction.

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