DEFORMABLE 2D-3D REGISTRATION

• US 20090052757A1
• Filed: 08/15/2008
• Published: 02/26/2009
• Est. Priority Date: 08/21/2007
• Status: Active Grant

• Current Assignee: Siemens Healthineers AG (Siemens AG)
• Original Assignee: Siemens Corporate Research Incorporated (Siemens AG)
• Inventors: Aharon, Shmuel, Fluck, Oliver, Khamene, Ali
• Granted Patent: US 8,184,886 B2
• Time in Patent Office: Days
• US Class Current: 382/131
• CPC Class Codes: A61B 6/032 Transmission computed tomography [CT]
• CPC Class Codes: A61B 6/5229 combining image data of a patient, e.g. combining a functional image with an anatomical image
• CPC Class Codes: A61B 6/5235 combining images from the same or different ionising radiation imaging techniques, e.g. PET and CT
• CPC Class Codes: A61N 2005/1062 using virtual X-ray images, e.g. digitally reconstructed radiographs [DRR]
• CPC Class Codes: A61N 5/103 Treatment planning systems
• CPC Class Codes: A61N 5/1049 for verifying the position of the patient with respect to the radiation beam
• CPC Class Codes: G06T 2207/10072 Tomographic images
• CPC Class Codes: G06T 2207/10124 Digitally reconstructed radiograph [DRR]
• CPC Class Codes: G06T 2207/30004 Biomedical image processing
• CPC Class Codes: G06T 7/30 Determination of transform parameters for the alignment of images, i.e. image registration
• CPC Class Codes: G06V 20/647 by matching two-dimensional images to three-dimensional objects

Abstract

A method for deformable registration including determining a vector field from a two-dimensional matching of a volume of an object of interest and a two-dimensional image of the object of interest, providing a deformation profile, and finding a volume deformation that maps to a state of the two-dimensional image, wherein the deformation is parameterized by the vector field and control points of the deformation profile to find a control point configuration of the volume deformation.

Claims

1. A computer implemented method for deformable registration comprising:

determining a vector field from a two-dimensional matching of a simulated two-dimensional image of a volume of an object of interest and a two-dimensional image of the object of interest;

providing a deformation profile comprising control points representing movement of the object of interest over time; and

finding a volume deformation that maps to a state of the two-dimensional image, wherein the deformation is parameterized by the vector field and the control points of the deformation profile to update a control point configuration of the simulated two-dimensional image of the volume of the object of interest.

2. The computer implemented method of claim 1, wherein the vector field maps differences between the simulated two-dimensional image of the volume of the object of interest and the two-dimensional image of the object of interest.

3. The computer implemented method of claim 1, wherein finding the volume deformation comprises:

a two-dimensional to three-dimensional back projection mapping the vector field to the deformation profile with respect to perspective distortion; and

generating a simulated three-dimensional deformation.

4. The computer implemented method of claim 3, further comprising a deformation for generating the simulated two-dimensional image of the volume of the object of interest from the simulated three-dimensional deformation.

5. A system for deformable two-dimensional to three-dimensional registration comprising:

a database for storing volumetric data of an object of interest; and

a processor for executing instructions of a plurality of modules processing the volumetric data, the modules comprising;

a volume deformation module generating a Digitally Reconstructed Radiograph (DRR) of the image from a deformed three-dimensional volume of the object of interest;

a two-dimensional matching module for performing a non-rigid registration in two-dimensions between the DDR and an actual two-dimensional image of the object of interest and generating a two-dimensional vector field; and

a two-dimensional to three-dimensional back projection module, connected to the two-dimensional matching module for receiving the two-dimensional vector field, mapping from the two-dimensional vector field as a control point grid to the deformed three-dimensional volume as a three-dimensional grid with respect to a perspective distortion.

6. The system of claim 5, further comprising a movement profile generation module for capturing volumetric data of the object of interest over time.

7. The system of claim 6, wherein the movement profile generation module registers the volumetric data of the object of interest over time outputting the deformed three-dimensional volume.

8. The system of claim 5, wherein the database stores a two-dimensional control point lookup texture.

10. The system of claim 9, wherein the texture includes a plurality of texture elements, each texture element storing a control point translation in respective channels.

11. A computer readable medium embodying instructions executable by a processor to perform a method for deformable registration comprising:

determining a vector field from a two-dimensional matching of a simulated two-dimensional image of a volume of an object of interest and a two-dimensional image of the object of interest;

providing a deformation profile comprising control points representing movement of the object of interest over time; and

finding a volume deformation that maps to a state of the two-dimensional image, wherein the deformation is parameterized by the vector field and the control points of the deformation profile to update a control point configuration of the simulated two-dimensional image of the volume of the object of interest.

12. The computer readable medium of claim 11, wherein the vector field maps differences between the simulated two-dimensional image of the volume of the object of interest and the two-dimensional image of the object of interest.

13. The computer readable medium of claim 11, wherein finding the volume deformation comprises:

a two-dimensional to three-dimensional back projection mapping the vector field to the deformation profile with respect to perspective distortion; and

generating a simulated three-dimensional deformation.

14. The computer readable medium of claim 13, further comprising a deformation for generating the simulated two-dimensional image of the volume of the object of interest from the simulated three-dimensional deformation.