TRANSDERMAL DRUG DELIVERY COMPOSITIONS AND TOPICAL COMPOSITIONS FOR APPLICATION ON THE SKIN
First Claim
1. A transdermal delivery composition for topical application on skin, the transdermal delivery composition comprising first and second penetrants, the first and second penetrants working synergistically and following disparate biochemical pathways, wherein the composition has a pH ranging from about 3.0 to about 7.4.
3 Assignments
0 Petitions
Accused Products
Abstract
Transdermal delivery compositions and topical compositions for application to the skin are provided. The transdermal delivery composition includes at least two penetrants working synergistically but by disparate biochemical pathways. In one embodiment, the transdermal delivery system includes benzyl alcohol and lecithin organogel. The transdermal delivery compositions are used in a variety of topical compositions as a means of transdermally delivering and topically administering different drugs and agents, including compositions promoting collagen biosynthesis, retinoids and skin lighteners, chemical denervation agents such as BOTOX®, anti-fungal agents, anesthetics and non-steroidal anti-inflammatory drugs (NSAIDs). In addition, these topical compositions may be used in combination with non-ablative treatment modalities, such as microdermabrasion, laser-based skin remodeling and radio-frequency-based skin remodeling.
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Citations
112 Claims
- 1. A transdermal delivery composition for topical application on skin, the transdermal delivery composition comprising first and second penetrants, the first and second penetrants working synergistically and following disparate biochemical pathways, wherein the composition has a pH ranging from about 3.0 to about 7.4.
- 14. A transdermal delivery composition for topical application to skin, the transdermal delivery composition comprising benzyl alcohol and lecithin organogel, wherein the benzyl alcohol is present in an amount greater than an amount of the lecithin organogel.
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103. A topical composition for promotion of collagen synthesis, the composition comprising:
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methionine; cysteine; a mixture of amino acids comprising leucine, lysine, phenylalanine, threonine, tryptophan, valine, histidine and arginine; at least one antioxidant; at least one cross-linking agent; and at least one metallic catalyst. - View Dependent Claims (104, 105, 106, 107, 109, 110, 111)
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Specification