Variable Sampling Interval for Blood Analyte Determinations
First Claim
1. A method of measuring an analyte in a patient, comprising:
- a. Measuring the value of the analyte at a first time;
b. Measuring the value of the analyte at a second time;
c. Where the second time is determined from at least one patient condition, at least one environmental condition, or a combination thereof.
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Abstract
The present invention provides methods and apparatuses that can provide measurement of glucose with variable intervals between measurements, allowing more efficient measurement with greater patient safety. A method according to the present invention can comprise measuring the value of an analyte such as glucose at a first time; determining a second time from a patient condition, an environmental condition, or a combination thereof; then measuring the value of the analyte at the second time (where the second time can be expressed as an interval after the first time, an absolute time, or a time indicated when certain patient or environmental conditions, or both, are reached or detected). The second time can be determined, as an example, from a comparison of the analyte value at the first time with a threshold. The interval between the first time and the second time can be related to the difference between the analyte value at the first time and the threshold; e.g., the closer to the threshold, the closer the two measurement times. The invention can be used with automated measurement systems, allowing the system to determine measurement times and automatically make measurements at the determined times, reducing operator interaction and operator error.
196 Citations
41 Claims
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1. A method of measuring an analyte in a patient, comprising:
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a. Measuring the value of the analyte at a first time; b. Measuring the value of the analyte at a second time; c. Where the second time is determined from at least one patient condition, at least one environmental condition, or a combination thereof. - View Dependent Claims (2, 3, 4, 5, 26, 27, 28)
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6. A method of measuring an analyte in a patient, comprising:
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a. Measuring the value of the analyte at a plurality of times, with each pair of successive measurements separated by a time interval; b. Wherein the time intervals are not all the same duration; c. And wherein at least one time interval is determined from at least one patient condition, or at least one environmental condition, or a combination thereof. - View Dependent Claims (7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25)
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29. An apparatus for measuring the value of an analyte at a plurality of times, comprising:
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a. A fluid access system, adapted to withdraw a sample of a bodily fluid from a patient; b. An analyte measurement system, adapted to measure the value of an analyte in a sample withdrawn from the patient by the fluid access system; c. A controller, adapted to respond to a patient condition, an environment condition, or a combination thereof, and to cause the fluid access system to withdraw a sample for measurement by the analyte measurement system. - View Dependent Claims (30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41)
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Specification