Sampling Device for Viscous Sample, Homogenization Method for Sputum and Method of Detecting Microbe
First Claim
1. A sampling device for a viscous sample, comprising:
- a tubular body with a closed distal end and an open proximal end, having a long straight middle section that is hollow inside, and a flange on an outer periphery of the proximal end;
a gasket inserted in the tubular body so that the gasket is brought into contact with an inner wall of the tubular body and slidable in a longitudinal direction along the tubular body;
a long rod-like plunger having a distal end serving as an engagement convex that engages with the gasket and a proximal end serving as an operation head adapted to slidably operate the gasket when the operation head is operated;
a plate-like nozzle that has substantially the same diameter as that of the straight middle section of the tubular body and is adapted to close the distal end of the tubular body; and
a slit formed in the plate-like nozzle, the slit having a predetermined shape adapted to serve as an aspiration and discharge port for aspirating and discharging the viscous sample.
1 Assignment
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Accused Products
Abstract
It is intended to provide: a sampling device for quantitatively sampling a liquid sample having a high viscosity such as sputum; an auxiliary jig therefor; an agent for homogenizing sputum by which sputum can be quickly treated under mild conditions and a microbe contained in the sputum can be detected at an improved stability; a homogenization device; a homogenization method; a method of detecting a microbe by using the above method; a separation device for conveniently, quickly and efficiently collecting a microbe contained in sputum; a method of collecting a microbe; and a method of detecting a microbe by using the above method. A sampling device for a viscous sample includes: a tubular body; a gasket; a long rod-like plunger; a plate-shaped nozzle that has substantially the same diameter as that of a straight section of the tubular body and is adapted to close a distal end of the tubular body; and a slit formed in the plate-like nozzle, the slit having a predetermined shape adapted to serve as an aspiration and discharge port for aspirating and discharging the viscous sample.
106 Citations
37 Claims
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1. A sampling device for a viscous sample, comprising:
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a tubular body with a closed distal end and an open proximal end, having a long straight middle section that is hollow inside, and a flange on an outer periphery of the proximal end; a gasket inserted in the tubular body so that the gasket is brought into contact with an inner wall of the tubular body and slidable in a longitudinal direction along the tubular body; a long rod-like plunger having a distal end serving as an engagement convex that engages with the gasket and a proximal end serving as an operation head adapted to slidably operate the gasket when the operation head is operated; a plate-like nozzle that has substantially the same diameter as that of the straight middle section of the tubular body and is adapted to close the distal end of the tubular body; and a slit formed in the plate-like nozzle, the slit having a predetermined shape adapted to serve as an aspiration and discharge port for aspirating and discharging the viscous sample. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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- 10. A homogenization agent for sputum, comprising cysteine protease.
- 14. A homogenization device for homogenizing sputum, comprising at least one particle containing at least one member selected from the group consisting of metals and oxides thereof.
- 18. A homogenization method for sputum, comprising stirring a sample containing subject sputum in the presence of at least one particle containing at least one member selected from the group consisting of metals and oxides thereof.
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26. A method of collecting a microbe from homogenized sputum, comprising:
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providing a separation device having at least three types of filters each allowing passage of a subject microbe and made of an organic material; and passing the homogenized sputum through the separation device to obtain a filtrate containing the subject microbe. - View Dependent Claims (27, 28, 29, 30, 31, 32, 33, 34, 36)
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Specification