SHELF STABLE, REDUCED CORROSION, READY TO USE PEROXYCARBOXYLIC ACID ANTIMICROBIAL COMPOSITIONS

• US 20090061017A1
• Filed: 08/30/2007
• Published: 03/05/2009
• Est. Priority Date: 08/30/2007
• Status: Active Grant

• Current Assignee: Ecolab USA Incorporated (Ecolab, Inc.)
• Original Assignee: Ecolab USA Incorporated (Ecolab, Inc.)
• Inventors: Molinaro, Katherine Joan, Besse, Michael, Pedersen, Daniel E.
• Granted Patent: US 9,271,494 B2
• Time in Patent Office: Days
• US Class Current: 424/616
• CPC Class Codes: A01N 2300/00 Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
• CPC Class Codes: A01N 25/22 containing ingredients stabilising the active ingredients
• CPC Class Codes: A01N 37/00 Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing cyclopropane carboxylic acids or derivatives thereof, e.g. cyclopropane carboxylic acid nitriles, A01N53/00
• CPC Class Codes: A01N 37/02 Saturated carboxylic acids or thio analogues thereof; Derivatives thereof
• CPC Class Codes: A01N 37/10 Aromatic or araliphatic carboxylic acids, or thio analogues thereof; Derivatives thereof
• CPC Class Codes: A01N 37/16 containing the group; Thio analogues thereof
• CPC Class Codes: A01N 37/38 having at least one oxygen or sulfur atom attached to an aromatic ring system
• CPC Class Codes: A01N 59/00 Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
• CPC Class Codes: A61L 2/186 Peroxide solutions
• CPC Class Codes: A61L 2202/24 Medical instruments, e.g. endoscopes, catheters, sharps

Abstract

The present invention relates to shelf stable and/or less corrosive peroxycarboxylic acid antimicrobial compositions, including ready-to-use compositions. Shelf stable compositions can include defined ratios of hydrogen peroxide to peroxycarboxylic acid and/or hydrogen peroxide to protonated carboxylic acid, but need not include strong acid. Reduced corrosion compositions can include carboxylic acid and corrosion inhibitor at acid pH. Compositions of the invention can have advantageous activity against spores.

Claims

1. A shelf stable, ready to use peroxycarboxylic acid composition comprising:

about 0.0001 to about 0.2 wt-% peroxycarboxylic acid;

about 1 to about 5 wt-% hydrogen peroxide; and

about 0.01 to about 5 wt-% carboxylic acid;

wherein;

the composition is free of added mineral acid;

the pH of the composition is about 1 to about 4;

the ratio of hydrogen peroxide;

peroxycarboxylic acid is about 30;

1 to about 60;

1; and

the ratio of hydrogen peroxide;

protonated carboxylic acid is about 1;

1 to about 2;

1.

2. The composition of claim 1, comprising:

about 0.005 to about 0.2 wt-% short chain peroxycarboxylic acid; and

about 0.5 to about 5 wt-% short chain carboxylic acid.

3. The composition of claim 1, comprising:

about 0.0001 to about 0.004 wt-% medium chain peroxycarboxylic acid; and

about 0.01 to about 0.3 wt-% medium chain carboxylic acid.

4. The composition of claim 1, further comprising buffer, sequestrant, hydrotrope, surfactant, corrosion inhibitor, or combination thereof.

5. The composition of claim 4, comprising about 0.01 to about 2 wt-% buffer, the buffer comprising phosphate salt, citrate salt, formate salt, malate salt, or acetate salt.

6. The composition of claim 4, comprising about 0.01 to about 2 wt-% buffer, the buffer being an acetate salt.

7. The composition of claim 4, comprising about 0.01 to about 0.25 wt-% corrosion inhibitor.

8. The composition of claim 7, wherein the corrosion inhibitor comprises a triazole corrosion inhibitor.

9. The composition of claim 8, wherein the corrosion inhibitor comprises benzotriazole.

10. The composition of claim 1, wherein the composition is sufficiently stable that greater than 85% of the initial concentration of peroxycarboxylic remains after 1 year of storage at room temperature and ambient humidity.

11. The composition of claim 1, further comprising about 0.01 to about 1 wt-% masking agent, the masking agent being chemically stable the composition for at least about 6 months at room temperature

14. The composition of claim 11, wherein the corrosion inhibitor comprises benzotriazole.

12. A low corrosion peroxycarboxylic acid composition comprising:

about 0.0001 to about 0.2 wt-% peroxycarboxylic acid;

about 1 to about 5 wt-% hydrogen peroxide;

about 0.01 to about 5 wt-% medium chain mono carboxylic acid or benzoic acid derivative;

about 0.01 to about 2 wt-% buffer; and

about 0.01 to about 0.25 wt-% corrosion inhibitor;

wherein;

the composition is free of added mineral acid;

the pH of the composition is about 1 to about 4.

13. The composition of claim 12, wherein the corrosion inhibitor comprises a triazole corrosion inhibitor.

15. The composition of claim 12, comprising about 0.01 to about 2 wt-% buffer, the buffer comprising phosphate salt, citrate salt, formate salt, malate salt, or acetate salt.

16. The composition of claim 12, comprising about 0.01 to about 2 wt-% buffer, the buffer being an acetate salt.

17. The composition of claim 12, comprising:

about 0.005 to about 0.2 wt-% short chain peroxycarboxylic acid; and

about 0.5 to about 5 wt-% short chain carboxylic acid.

18. The composition of claim 12, comprising:

about 0.0001 to about 0.004 wt-% medium chain peroxycarboxylic acid; and

about 0.01 to about 0.3 wt-% medium chain carboxylic acid.

19. The composition of claim 12, further comprising sequestrant, hydrotrope, surfactant, or combination thereof.

20. The composition of claim 12, wherein:

the ratio of hydrogen peroxide;

peroxycarboxylic acid is about 30;

1 to about 60;

1; and

the ratio of hydrogen peroxide;

protonated carboxylic acid is about 1;

1 to about 2;

1.

21. The composition of claim 12, wherein the composition causes less than 200 mil per year corrosion of brass when evaluated according to ASTM G1-90 or ASTM G31-72.

22. The composition of claim 12, further comprising about 0.01 to about 1 wt-% masking agent, the masking agent being chemically stable the composition for at least about 6 months at room temperature

23. A method of reducing the population of bacterial endospores, comprising:

contacting bacterial endospores with a composition comprising;

about 0.0001 to about 0.2 wt-% peroxycarboxylic acid;

about 1 to about 5 wt-% hydrogen peroxide; and

about 0.01 to about 5 wt-% carboxylic acid;

wherein;

the composition is free of added mineral acid;

the pH of the composition is about 1 to about 4;

the ratio of hydrogen peroxide;

peroxycarboxylic acid is about 30;

1 to about 60;

1; and

the ratio of hydrogen peroxide;

protonated carboxylic acid is about 1;

1 to about 2;

1; and

achieving greater than 5 log reduction in the population of bacterial endospores in less than 1 hour under ambient conditions.