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Therapeutic use of cpg oligodeoxynucleotide for skin disease

  • US 20090062224A1
  • Filed: 11/04/2005
  • Published: 03/05/2009
  • Est. Priority Date: 11/05/2004
  • Status: Active Grant
First Claim
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1. A method for inhibiting a Th2 cytokine and/or inducing a Th1 cytokine, comprising administering to a subject in need thereof an effective amount of a CpG oligodeoxynucleotide represented by the following formula:

  • [formula] SYYSSACGTTSNYRAWMYTC (SEQ ID NO.

         1)wherein, S is G or C;

    Y is C or T;

    N is any one selected from the group consisting of A, G, T and C;

    R is G or A;

    W is A or T; and

    M is A or C, and wherein the CpG oligodeoxynucleotide comprises at least two unmethylated CpG motifs.

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