PERIODIC SAMPLING OF CARDIAC SIGNALS USING AN IMPLANTABLE MONITORING DEVICE

• US 20090062671A1
• Filed: 08/04/2008
• Published: 03/05/2009
• Est. Priority Date: 08/02/2007
• Status: Abandoned Application

• Current Assignee: Greatbatch Limited (Greatbatch Incorporated)
• Original Assignee: Greatbatch Limited (Greatbatch Incorporated)
• Inventors: Belalcazar, Andres, Brockway, Brian P.
• Application Number:
  US12/185,459
• Publication Number:
  US 20090062671A1
• Time in Patent Office: Days
• US Class Current: 600/518
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/361 Detecting fibrillation
• CPC Class Codes: A61N 1/395 for treating atrial fibrillation

Abstract

In a method of diagnosing an atrial fibrillation or atrial flutter condition, a monitoring device implanted in a subject acquires strips of a subcutaneous ECG signal of a predetermined length. The strips are acquired at regular, periodic intervals, and the timing of when the strips are acquired is not triggered by analysis of the subcutaneous ECG signal by the monitoring device. The acquired subcutaneous ECG strips are stored in memory of the implanted monitoring device, and transmitted from the implanted monitoring device for receipt by an external analysis system. In the external analysis system, the received subcutaneous ECG strips are processed to generate information for an assessment of an atrial fibrillation or atrial flutter burden for the subject.

Claims

1. A method of diagnosing an atrial fibrillation or atrial flutter condition, comprising:

acquiring, using a monitoring device implanted in a subject, strips of a subcutaneous ECG signal of a predetermined length, wherein the strips are acquired at regular, periodic intervals, and wherein the timing of when the strips are acquired is not triggered by analysis of the subcutaneous ECG signal by the monitoring device;

storing the acquired subcutaneous ECG strips in memory of the implanted monitoring device;

transmitting the acquired subcutaneous ECG strips from the implanted monitoring device for receipt by an external analysis system; and

processing, in the external analysis system, the received subcutaneous ECG strips to generate information for an assessment of an atrial fibrillation or atrial flutter burden for the subject.

2. The method of claim 1, wherein the predetermined length of the strips is in a range of about 3 to 120 seconds.

3. The method of claim 2, wherein the predetermined length of the strips is in a range of about 3 to 30 seconds.

4. The method of claim 1, wherein the regular, periodic intervals have a programmable length in a range of about 3 to 120 minutes.

5. The method of claim 4, wherein the regular, periodic intervals have a programmable length in a range of about 3 to 30 minutes.

6. The method of claim 5, wherein the regular, periodic intervals have a programmable length in a range of about 3 to 10 minutes.

7. The method of claim 1, wherein the assessment of an atrial fibrillation or atrial flutter burden is performed by the external analysis system.

8. The method of claim 1, wherein the assessment of an atrial fibrillation or atrial flutter burden is performed by a human.

9. The method of claim 1, wherein the monitoring device enters a low power mode of operation between acquisition of successive strips of the subcutaneous ECG signal.

10. The method of claim 1, wherein the processing comprises estimating a duration of an atrial fibrillation or atrial flutter episode.

11. The method of claim 10, wherein the information includes, for a given time period, an estimation of time within the period that the subject experienced atrial fibrillation or atrial flutter.

12. An implantable monitoring device for implantation in a subject, comprising:

sense electrodes for sensing a subcutaneous ECG signal;

circuitry that causes strips of the subcutaneous ECG signal of a predetermined length to be acquired using the sense electrodes, wherein the circuitry causes the strips to be acquired at regular, periodic intervals, and wherein the timing of when the strips are acquired is not triggered by analysis of the subcutaneous ECG signal by the implantable monitoring device;

memory in which the strips of the subcutaneous ECG signal are stored; and

a transmitter that transmits the acquired strips for receipt by an external analysis system and processing, in the external analysis system, the received strips to generate information for an assessment of an atrial fibrillation or atrial flutter burden for the subject.

13. The implantable monitoring device of claim 12, wherein the predetermined length of the strips is in a range of about 3 to 120 seconds.

14. The implantable monitoring device of claim 13, wherein the predetermined length of the strips is in a range of about 3 to 30 seconds.

15. The implantable monitoring device of claim 14, wherein the regular, periodic intervals have a programmable length in a range of about 3 to 120 minutes.

16. The implantable monitoring device of claim 15, wherein the regular, periodic intervals have a programmable length in a range of about 3 to 30 minutes.

17. The implantable monitoring device of claim 12, further comprising circuitry that causes the device to enter a low power mode of operation between acquisition of successive strips of the subcutaneous ECG signal.

18. A system for detecting atrial arrhythmia in an ambulatory subject, comprising:

an implantable monitoring device that includes;

sense electrodes for sensing a subcutaneous ECG signal;

circuitry that causes strips of the subcutaneous ECG signal of a predetermined length to be acquired using the sense electrodes, wherein the circuitry causes the strips to be acquired at regular, periodic intervals, and wherein the timing of when the strips are acquired is not triggered by analysis of the subcutaneous ECG signal by the implantable monitoring device;

memory in which the strips of the subcutaneous ECG signal are stored; and

a transmitter that transmits the acquired strips; and

a remote computing device that includes a receiver for receiving the transmitted strips, and an analysis module to generate information for an assessment of an atrial fibrillation or atrial flutter burden for the subject.

19. The system of claim 18, wherein a human provides the assessment of an atrial fibrillation or atrial flutter burden for the subject by reviewing the generated information.