CONTROL OF BODY FLUID CONDITION USING DIURETICS, BASED ON BIOLOGICAL PARAMETERS

• US 20090062730A1
• Filed: 08/29/2008
• Published: 03/05/2009
• Est. Priority Date: 09/01/2007
• Status: Abandoned Application

• Current Assignee: San Hoon Woo
• Original Assignee: San Hoon Woo
• Inventors: Woo, San Hoon
• Application Number:
  US12/202,094
• Publication Number:
  US 20090062730A1
• Time in Patent Office: Days
• US Class Current: 604/66
• CPC Class Codes: A61M 2202/0496 Urine
• CPC Class Codes: A61M 2205/05 combined with other kinds of therapy
• CPC Class Codes: A61M 2205/3569 sublocal, e.g. between console and disposable
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61M 5/16827 controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths infusion of multiple fluids without using a controller A61M5/1407
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00

Abstract

The system for controlling body fluids overcomes the limitations of the prior art by automatically infusing diuretic and/or other drugs into a human patient. In one approach, the rate of infusion of the diuretic is adjusted based on a measured biological parameter of the patient. For example, this biological parameter can be transmitted wirelessly to a portable diuretic infusion device attached to the patient.

Claims

1. A diuretic infusion system comprising:

a biological parameter measurement apparatus including;

a biological parameter measurement sensor for measuring a biological parameter of a human patient; and

a diuretic infusion device including;

a reservoir for holding a diuretic;

a pump connected to the reservoir and connectable to the human patient, for infusing diuretic from the reservoir into the human patient; and

a controller for controlling the pump and rate of infusion of the diuretic based on the measured biological parameter.

2. The system of claim 1, wherein:

the biological parameter measurement apparatus further includes a wireless transmitter for wirelessly transmitting measured biological information; and

the diuretic infusion device further includes a wireless receiver for wirelessly receiving the biological parameter information transmitted by the biological parameter measurement apparatus, the controller controlling the pump and rate of infusion of the diuretic based on the received biological parameter information.

3. The system of claim 1, wherein the biological parameter measurement sensor is a patch sensor.

4. The system of claim 1, wherein the biological parameter measurement sensor is an intracardiac pressure measurement sensor and the controller adjusts the rate of infusion based on a measured pressure within a cardiac chamber of the patient.

5. The system of claim 4, wherein the controller adjusts the rate of infusion based on the measured pressure within the cardiac chamber to maintain a target pressure in the cardiac chamber.

6. The system of claim 1, wherein the biological parameter measurement sensor is an intravascular pressure measurement sensor and the controller adjusts the rate of infusion based on a measured pressure within a blood vessel of the patient.

7. The system of claim 6, wherein the controller adjusts the rate of infusion based on the measured pressure within the blood vessel to maintain a target pressure in the blood vessel.

8. The system of claim 1, wherein the biological parameter measurement sensor is an intrathoracic electrical impedance measurement sensor and the controller adjusts the rate of infusion based on a measured intrathoracic electrical impedance.

9. The system of claim 1, wherein the biological parameter measurement apparatus is a non-invasive blood pressure measurement device. and the controller adjusts the rate of infusion based on a measured blood pressure of the patient

10. The system of claim 1 wherein the biological parameter measurement apparatus is coupled to a pacemaker.

11. The system of claim 1 wherein the biological parameter measurement apparatus is coupled to an implantable cardioverter defibrillator.

12. The system of claim 1 wherein the biological parameter measurement apparatus is coupled to a cardiac resynchronization therapy.

13. The system of claim 1, wherein the biological parameter is a biomarket and the controller adjusts the rate of infusion based on the measured biomarker.

14. The system of claim 13, wherein the biomarker is selected from the group consisting of an atrial natriuretic peptide, a brain natriuretic peptide, and a NT-pro brain natriuretic peptide.

15. The system of claim 1, wherein the system is further configured for administering a drug selected from a group consisting of:

ACE inhibitor, calcium channel blocker, beta blocker, inotropic agent, hydralazine, loop diuretics, thiazide diuretics, and vasopressin receptor antagonist

16. The system of claim 1, wherein the pump is a portable pump.

17. The system of claim 1, wherein the pump is a non-portable pump.

18. The system of claim 1, wherein the pump is an ambulatory drug infusion pump.

19. The system of claim 1, wherein the pump is an implantable drug infusion pump.

20. A method for infusing diuretic to a human patient comprising:

receiving non-weight biological parameter information based on measurements of a non-weight biological parameter for a patient; and

adjusting an infusion rate of diuretic into the patient based on the measured non-weight biological parameter according to a predetermined protocol.