COMPOSITE STENT WITH POLYMERIC COVERING AND BIOACTIVE COATING
First Claim
Patent Images
1. A composite expandable device for delivery into a vessel carrying blood comprising:
- an expandable support frame having first and second end portions,a polymer sleeve extending over the support frame and having inner and outer surfaces, anda coating disposed on and covalently attached to at least one of the inner and outer surfaces of the polymer sleeve and covalently bonded to a cell-adesion peptide through multifunctional linkers/spacers ending in COOH for enhancing endothelial cell growth on the device, wherein linkers ending in COOH reduces a thrombogenic risk presented by unbound linkers.
0 Assignments
0 Petitions
Accused Products
Abstract
A composite expandable stent for delivery into a vessel carrying blood comprising an expandable support frame having first and second end portions. A porous imprevious polymer sleeve having inner and outer surfaces extending over the support frame. A coating is disposed on at least one of the inner and outer surfaces of the polymer sleeve for enhancing endothelial cell growth on the device and polymer sleeve. The stent can be cylindrical or tapered.
-
Citations
20 Claims
-
1. A composite expandable device for delivery into a vessel carrying blood comprising:
-
an expandable support frame having first and second end portions, a polymer sleeve extending over the support frame and having inner and outer surfaces, and a coating disposed on and covalently attached to at least one of the inner and outer surfaces of the polymer sleeve and covalently bonded to a cell-adesion peptide through multifunctional linkers/spacers ending in COOH for enhancing endothelial cell growth on the device, wherein linkers ending in COOH reduces a thrombogenic risk presented by unbound linkers. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
-
Specification