BIOSENSOR
First Claim
1. A biosensor which, having a reagent layer including a reagent which reacts specifically with a specific component in a sample solution, measures the concentration of the specific component in the sample solution,said reagent layer including glucose dehydrogenase having flavin adenine dinucleotide as a coenzyme, and an organic acid or its salt having at least one carboxyl group in a molecule thereof.
2 Assignments
0 Petitions
Accused Products
Abstract
In a biosensor for measuring glucose in a liquid sample, an additive agent which is one of an organic acid or organic acid salt having at least one carboxyl group in a molecule, an organic acid or organic acid salt having at least one amino group or carbonyl group in a molecule, a sugar alcohol, and a solubilized protein, or a combination thereof is added into a reagent layer including glucose dehydrogenase having flavin adenine dinucleotide as a coenzyme, which is provided on an insulating substrate. Thereby, the substrate specificity to glucose and the preservation stability can be enhanced, and further, reactions to sugars other than glucose can be avoided.
23 Citations
27 Claims
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1. A biosensor which, having a reagent layer including a reagent which reacts specifically with a specific component in a sample solution, measures the concentration of the specific component in the sample solution,
said reagent layer including glucose dehydrogenase having flavin adenine dinucleotide as a coenzyme, and an organic acid or its salt having at least one carboxyl group in a molecule thereof.
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7. A biosensor which, having a reagent layer including a reagent which reacts specifically with a specific component in a sample solution, measures the concentration of the specific component in the sample solution,
said reagent layer including glucose dehydrogenase having flavin adenine dinucleotide as a coenzyme, and an organic acid or its salt having at least one amino group or carbonyl group in a molecule thereof.
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13. A biosensor which, having a reagent layer including a reagent which reacts specifically with a specific component in a sample solution, measures the concentration of the specific component in the sample solution,
said reagent layer including glucose dehydrogenase having flavin adenine dinucleotide as a coenzyme, and a sugar alcohol.
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19. A biosensor which, having a reagent layer including a reagent which reacts specifically with a specific component in a sample solution, measures the concentration of the specific component in the sample solution,
said reagent layer including glucose dehydrogenase having flavin adenine dinucleotide as a coenzyme, and a solubilized protein.
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24. A biosensor which, having a reagent layer including a reagent which reacts specifically with a specific component in a sample solution, measures the concentration of the specific component in the sample solution,
said reagent layer including glucose dehydrogenase having flavin adenine dinucleotide as a coenzyme, and at least two additive agents among an organic acid or its salt having at least one carboxyl group in a molecule thereof, an organic acid or its salt having at least one amino group or carbonyl group in a molecule thereof, a sugar alcohol, and a solubilized protein.
Specification