THREE-DIMENSIONAL (3D) HYDRODYNAMIC FOCUSING USING A MICROFLUIDIC DEVICE
First Claim
Patent Images
1. An apparatus, the apparatus being a microfluidic device comprising:
- a substrate, the substrate being generally planar;
a sample flow inlet, configured to receive a sample flow;
a first flow inlet, configured to receive a first sheath flow; and
a curved channel, the curved channel configured to receive the sample flow and the first sheath flow,the sample flow inlet, the first flow inlet, and the curved channel being supported by the substrate, the curved channel being generally parallel to the substrate,the curved channel being configured to provide out-of-plane hydrodynamic focusing of the sample flow,the sample flow being compressed along a direction normal to the substrate.
2 Assignments
0 Petitions
Accused Products
Abstract
A microfluidic device comprises inlets for a sample flow and an out-of-plane focusing sheath flow, and a curved channel section configured to receive the sample flow and out-of-plane focusing sheath and to provide hydrodynamic focusing of the sample flow in an out-of-plane direction, the out-of-plane direction being normal to a plane including the curved channel.
-
Citations
18 Claims
-
1. An apparatus, the apparatus being a microfluidic device comprising:
-
a substrate, the substrate being generally planar; a sample flow inlet, configured to receive a sample flow; a first flow inlet, configured to receive a first sheath flow; and a curved channel, the curved channel configured to receive the sample flow and the first sheath flow, the sample flow inlet, the first flow inlet, and the curved channel being supported by the substrate, the curved channel being generally parallel to the substrate, the curved channel being configured to provide out-of-plane hydrodynamic focusing of the sample flow, the sample flow being compressed along a direction normal to the substrate. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
-
-
12. An apparatus, the apparatus being a planar microfluidic device configured to receive a sample flow and a first sheath flow,
the apparatus including a curved channel supported by and generally parallel to a planar substrate, the curved channel being configured to provide out-of-plane hydrodynamic focusing of the sample flow, the sample flow being compressed in a direction normal to the planar substrate.
-
15. A method of hydrofluidic focusing a sample flow in a planar microfluidic device having a planar substrate, the method comprising:
passing the sample flow and a sheath flow through a curved channel section disposed on the planar substrate, the curved channel section providing hydrofluidic focusing of the sample flow in a direction generally normal to the planar substrate. - View Dependent Claims (16, 17, 18)
Specification