Transient Decay Amperometry
First Claim
1. A method for determining an analyte concentration in a sample, comprising:
- introducing the sample to a sensor strip;
applying a signal to the sample after an incubation period of at most 8 seconds;
generating a signal having a transient decay in response to a redox reaction of a measurable species; and
determining the analyte concentration from the transient decay of the generated signal.
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Accused Products
Abstract
A biosensor system determines an analyte concentration of a biological sample using an electrochemical process without Cottrell decay. The biosensor system generates an output signal having a transient decay, where the output signal is not inversely proportional to the square root of the time. The transient decay is greater or less than the −0.5 decay constant of a Cottrell decay. The transient decay may result from a relatively short incubation period, relatively small sample reservoir volumes, relatively small distances between electrode surfaces and the lid of the sensor strip, and/or relatively short excitations in relation to the average initial thickness of the reagent layer. The biosensor system determines the analyte concentration from the output signal having a transient decay.
108 Citations
25 Claims
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1. A method for determining an analyte concentration in a sample, comprising:
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introducing the sample to a sensor strip; applying a signal to the sample after an incubation period of at most 8 seconds; generating a signal having a transient decay in response to a redox reaction of a measurable species; and determining the analyte concentration from the transient decay of the generated signal. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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19. A method for determining an analyte concentration in a sample, comprising:
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applying a signal to the sample, the signal including at least three excitations, each excitation having a duration from 0.1 to 5 seconds; generating a signal having a transient decay in response to a redox reaction of a measurable species; and determining the analyte concentration from the transient decay of the generated signal. - View Dependent Claims (20, 21, 22, 23, 24, 25)
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Specification