Analyte Monitoring Device and Methods of Use
First Claim
1. A sensor control unit comprising:
- a housing adapted for placement on skin and adapted to receive a portion of an electrochemical sensor having a plurality of contact pads;
a plurality of conductive contacts disposed on the housing and configured for coupling to the plurality of contact pads on the sensor; and
a transmitter disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor.
0 Assignments
0 Petitions
Accused Products
Abstract
An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor.
289 Citations
179 Claims
-
1. A sensor control unit comprising:
-
a housing adapted for placement on skin and adapted to receive a portion of an electrochemical sensor having a plurality of contact pads; a plurality of conductive contacts disposed on the housing and configured for coupling to the plurality of contact pads on the sensor; and a transmitter disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor.
-
-
2-120. -120. (canceled)
-
121. An analyte sensor configured for measuring an analyte in a host, the sensor comprising:
-
a first working electrode disposed beneath an active enzymatic portion of a sensor membrane; and a second working electrode disposed beneath an inactive enzymatic portion of a sensor membrane or a non enzymatic portion of a sensor membrane, wherein the sensor membrane comprises an interference domain located over the first working electrode and the second working electrode, wherein the interference domain is configured to substantially block flow of at least one interfering species. - View Dependent Claims (122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142)
-
-
143. An analyte sensor configured for measuring glucose in a host, the sensor comprising:
-
a first working electrode configured to generate a first signal indicative of glucose and non glucose related electroactive compounds having a first oxidation potential; and a second working electrode configured to generate a second signal indicative of non glucose related electroactive compounds having the first oxidation potential; and electronics configured to process the first signal and the second signal, wherein the sensor further comprises at least two mechanisms configured to substantially block or substantially eliminate noise in the sensor signal, the mechanisms comprising a first mechanism disposed on the sensor and configured to reduce or substantially block interferants from reaching the first working electrode and the second working electrode, and a second mechanism in the electronics comprising programming configured to process the first signal to substantially eliminate the signal associated with the non glucose related electroactive compounds therefrom. - View Dependent Claims (144, 145, 146, 147, 148, 149)
-
-
150. A method for providing a substantially noise free signal for a glucose sensor implanted in a host, the method comprising:
-
implanting a glucose sensor in a host, the glucose sensor comprising; a first working electrode disposed beneath an active enzymatic portion of a sensor membrane; and a second working electrode disposed beneath an inactive enzymatic or a non enzymatic portion of a sensor membrane, wherein the sensor is configured to substantially block one or more interferants from reaching the first working electrode and the second working electrode; generating a first signal indicative of glucose and non glucose related electroactive compounds having a first oxidation potential; generating a second signal indicative of non glucose related electroactive compounds having the first oxidation potential; and processing the first signal to substantially eliminate the signal associated with the non glucose related electroactive compounds therefrom.
-
-
151. An analyte sensor configured for measuring an analyte in a host, the sensor comprising:
-
a first working electrode disposed beneath an active enzymatic portion of a sensor membrane; and a second working electrode disposed beneath an inactive enzymatic portion of a sensor membrane or a non enzymatic portion of a sensor membrane, wherein the sensor membrane comprises an interference domain located over the first working electrode and the second working electrode, wherein the interference domain is configured to substantially block flow of at least one interfering species, and wherein the interference domain comprises a material selected from the group consisting of polyurethane, silicone and a cellulosic polymer. - View Dependent Claims (152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164)
-
-
165. An analyte sensor configured for measuring an analyte in a host, the sensor comprising:
-
a first working electrode disposed beneath an active enzymatic portion of a sensor membrane; and a second working electrode disposed beneath an inactive enzymatic portion of a sensor membrane or a non enzymatic portion of a sensor membrane, wherein the sensor membrane comprises an interference domain located over the first working electrode and the second working electrode, wherein the interference domain is configured to substantially block flow of at least one interfering species, and wherein the interference domain comprises an auxiliary layer comprising a conductive material, wherein the auxiliary layer is configured to modify an electrochemical interferant such that the electrochemical interferent is rendered substantially electrochemically non-reactive at the working electrodes. - View Dependent Claims (166)
-
-
167. An analyte sensor configured for measuring an analyte in a host, the sensor comprising:
-
a first working electrode disposed beneath an active enzymatic portion of a sensor membrane; and a second working electrode disposed beneath an inactive enzymatic portion of a sensor membrane or a non enzymatic portion of a sensor membrane, wherein the sensor membrane comprises an interference domain located over the first working electrode and the second working electrode, wherein membrane comprises at least one enzyme configured to metabolize at least one interferent, wherein the enzyme is selected from the group consisting of a peroxidase and an oxidase. - View Dependent Claims (168, 169)
-
-
170. An continuous glucose monitoring system configured for measuring glucose in a host, the system comprising:
-
a continuous glucose sensor comprising; a first working electrode configured to generate a first signal indicative of glucose and non-glucose related electroactive compounds having a first oxidation potential; and a second working electrode configured to generate a second signal indicative of non-glucose related electroactive compounds having the first oxidation potential; and electronics configured to process the first signal and the second signal; wherein the sensor further comprises at least two mechanisms configured to substantially block or substantially eliminate noise in the sensor signal, the mechanisms comprising a first mechanism disposed on the sensor and configured to reduce or substantially block interferants from reaching the first working electrode and the second working electrode, and a second mechanism in the electronics comprising programming configured to process the first signal to substantially eliminate a signal associated with the non-glucose related electroactive compounds therefrom. - View Dependent Claims (171, 172, 173, 174, 175, 176, 177, 178, 179)
-
Specification