INFUSION THERAPY SENSOR SYSTEM

• US 20090069743A1
• Filed: 09/11/2008
• Published: 03/12/2009
• Est. Priority Date: 09/11/2007
• Status: Abandoned Application

• Current Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Original Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Inventors: NIU, SANJUN, KRISHNAMOORTHY, SIVARAMAKRISHNAN, MEINZER, RANDOLPH R., BUI, TUAN, LAL, BIRENDRA K.
• Application Number:
  US12/208,367
• Publication Number:
  US 20090069743A1
• Time in Patent Office: Days
• US Class Current: 604/66
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1459 invasive, e.g. introduced into the body by a catheter A61B5/1464 takes precedence
• CPC Class Codes: A61B 5/1473 invasive, e.g. introduced into the body by a catheter A61B5/1482 takes precedence
• CPC Class Codes: A61B 5/15003 for venous or arterial blood
• CPC Class Codes: A61B 5/150099 by negative pressure, other than vacuum extraction into a syringe by pulling on the piston rod or into pre-evacuated tubes
• CPC Class Codes: A61B 5/150213 Venting means
• CPC Class Codes: A61B 5/150221 Valves
• CPC Class Codes: A61B 5/150229 Pumps for assisting the blood sampling
• CPC Class Codes: A61B 5/150236 Pistons, i.e. cylindrical bodies that sit inside the syringe barrel, typically with an air tight seal, and slide in the barrel to create a vacuum or to expel blood
• CPC Class Codes: A61B 5/150244 Rods for actuating or driving the piston, i.e. the cylindrical body that sits inside the syringe barrel, typically with an air tight seal, and slides in the barrel to create a vacuum or to expel blood
• CPC Class Codes: A61B 5/150389 Hollow piercing elements, e.g. canulas, needles, for piercing the skin
• CPC Class Codes: A61B 5/150503 Single-ended needles hollow piercing element tip design A61B5/150396, needle sets for catheters A61M25/06, needles for bringing media into the body A61M5/32
• CPC Class Codes: A61B 5/150755 Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
• CPC Class Codes: A61B 5/15087 short range, e.g. between console and disposable using implanted devices A61B5/150877
• CPC Class Codes: A61B 5/150992 Blood sampling from a fluid line external to a patient, such as a catheter line, combined with an infusion line; blood sampling from indwelling needle sets, e.g. sealable ports, luer couplings, valves tubing connectors and couplings A61M39/00
• CPC Class Codes: A61B 5/153 Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
• CPC Class Codes: A61B 5/155 Devices specially adapted for continuous or multiple sampling, e.g. at predetermined intervals devices loaded with multiple lancets simultaneously A61B5/15146
• CPC Class Codes: A61B 5/157 Devices characterised by integrated means for measuring characteristics of blood
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61M 2205/3303 Using a biosensor
• CPC Class Codes: A61M 2205/3306 : Optical measuring means
• CPC Class Codes: A61M 2205/3313 : used specific wavelengths
• CPC Class Codes: A61M 25/007 : Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
• CPC Class Codes: A61M 5/14212 : Pumping with an aspiration and an expulsion action
• CPC Class Codes: A61M 5/1723 : using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00

Abstract

A sensor system for use with an infusion system may include at least one sensor disposed within a catheter, the at least one sensor comprising at least one of an optical sensor, an electrical sensor or a chemical/biochemical sensor. The sensor system may instead include a sample cell that is in fluid communication with the infusion system, which sample cell may be used with an analyzer to determine a patient'"'"'s condition. The sensor system may be integrated with a control system for an infusion pump to control operation of the pump.

Claims

1. An integrated sensor system for providing information to a control system, comprising:

a catheter configured for communication with the control system, the catheter forming at least one lumen; and

at least one sensor disposed within the catheter, the at least one sensor comprising at least one of an optical sensor, an electrical sensor or a chemical/biochemical sensor.

2. The integrated sensor system of claim 1, where in the catheter further comprises side ports to enable blood flow into the at least one lumen to perform sensing

3. The integrated sensor system of claim 1, wherein the at least one sensor comprises an optical sensor having at least one optical fiber for emitting light and at least one optical fiber for collecting light.

4. The integrated sensor system of claim 1, wherein the at least one sensor comprises an electrical sensor having an anode, a cathode and a reference electrode.

5. The integrated sensor system of claim 1, wherein the at least one sensor comprises a chemical/biochemical sensor generating an optical or electrical signal according to a chemical or biochemical reaction.

6. An integrated sensor system, comprising:

an infusion pump;

a control system operably connected to the infusion pump;

a multi-lumen catheter in fluid communication with the infusion pump; and

at least one sensor disposed within the catheter, the at least one sensor comprising at least one of an optical sensor, an electrical sensor or a chemical/biochemical sensor, the sensor operably connected to the control system,

wherein the control system is configured to receive and process input signals from the at least one sensor and to provide an output useful for a real-time diagnosis.

7. A sensor system comprising:

a sample cell including opposing walls spaced from each other to define a test region therebetween and an inlet in fluid communication with the test region; and

an analyzer including;

a housing comprising a holder in which at least the test region of the sample cell is received,

a light emitter and a light receptor, the light emitter and the light receptor disposed about the holder adjacent to the test region;

a processor operatively coupled to the light receptor to receive a sensor signal therefrom, the processor programmed to determine a physical condition of a patient according to the sensor signal; and

signaling device operatively coupled to the processor to receive a processor signal therefrom, the signaling device provides an indication associated with the physical condition of the patient according to the processor signal.

8. The sensor system of claim 7, further comprising an extension set, the extension set having an administration set connector and a catheter hub connector, the sample cell formed with the extension set between the administration set connector and the catheter hub connector.

9. The sensor system of claim 8, further comprising an administration set coupled to the extension set and a reversible pump operatively coupled to the administration set, the pump having a forward state to pass fluid through the extension set from the administration set connector to the catheter hub connector and a reverse state to pass fluid through the extension set from the catheter hub connector to the administration set connector.

10. The sensor system of claim 8, wherein the extension set comprises a flexible diaphragm disposed between the administration set connector and the sample cell, the diaphragm moveable between a depressed state and a distended state to draw fluid into the sample cell.

11. The sensor system of claim 10, wherein the extension set comprises at least one on-off clamp, the on-off clamp open to permit fluid to flow in the direction from the administration set connector to the catheter hub connector and closed to limit flow in the direction from the catheter hub connector to the administration set connector.

12. The sensor system of claim 11, further comprising a frame, the sample cell, the diaphragm, and the at least one on-off clamp being attached to the frame, the frame having a first port coupled to the extension set connector and a second port coupled to the catheter hub connector.

13. The sensor system of claim 7, wherein the at least one of the opposing walls is defined in whole or in part by quartz or ultraviolet-grade fused silica.

14. The sensor system of claim 7, wherein the sample cell is open only at the inlet, and the inlet is attached to a catheter hub connector.

15. The sensor system of claim 7, wherein the light emitter and the light receptor are disposed in the housing to define a peripheral device, the peripheral device being detached from the processor.

16. The sensor system of claim 15, wherein the peripheral device is operatively coupled to the processor by a length of cable.

17. The sensor system of claim 15, wherein the peripheral device comprises a wireless transmitter coupled to the light receptor and the processor has a wireless receiver coupled thereto and in wireless communication with the wireless transmitter.

18. A sensor system disposable including:

an administration set connector;

a catheter hub connector; and

a sensor cell including opposing walls spaced from each other to define a test region therebetween, the sample cell connected at a first end to the administration set connector and at a second end to the catheter hub connector.

19. The sensor system disposable of claim 18, further comprising a flexible diaphragm disposed between the administration set connector and the sample cell, the diaphragm moveable between a depressed state and a distended state to draw fluid into the sample cell.

20. The sensor system disposable of claim 19, wherein the extension set comprises at least one on-off clamp, the at least one on-off clamp open to permit fluid to flow in the direction from the administration set connector to the catheter hub connector and closed to limit flow in the direction from the catheter hub connector to the administration set connector.

21. The sensor system disposable of claim 20, further comprising a frame, the sample cell, the diaphragm, and the at least one on-off clamp being attached to the frame, the frame having a first port coupled to the extension set connector and a second port coupled to the catheter hub connector.