MICRO FLUIDICS MANIFOLD APPARATUS
First Claim
1. A manifold device for use with a valve assembly, an aspiration source and a dispensing source to transfer fluid from at least one of a plurality of fluid reservoirs to at least one test site on a substrate surface, said valve assembly including a rotor face defining a plurality of discrete communication channels each movable as a unit between an aspiration condition and a dispensing condition as the valve assembly rotates relative its rotational axis, said manifold device comprising:
- a manifold body defining a plurality of fluid aspiration conduits each having a first aspiration port in fluid communication with the aspiration source, and a second aspiration port in selective fluid communication with a corresponding communication channel of the valve assembly to aspirate a respective liquid sample slug from a corresponding reservoir of sample fluid into discrete sample paths when the valve assembly is in the aspiration condition, said manifold body further defining a plurality of fluid dispensing conduits each having a respective first dispensing port in fluid communication with the dispensing source, and a second dispensing port in selective fluid communication with a corresponding communication channel of the valve assembly to selectively dispense at least one droplet of the corresponding liquid sample slug from the corresponding sample path when the valve assembly is in the dispensing condition,wherein, in the aspiration condition, said respective sample paths are out of fluid communication with the dispensing source and, in the dispensing condition, said respective sample paths are out of fluid communication with the aspiration source.
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Accused Products
Abstract
A manifold device is provided for use with a valve assembly, an aspiration source and a dispensing source to transfer fluid from at least one of a plurality of fluid reservoirs to at least one test site on a substrate surface. The manifold device includes a manifold body that defines a plurality of fluid aspiration conduits, for fluid aspiration in an aspiration position, and a plurality of fluid dispensing conduits to selectively dispense at least one droplet of the corresponding liquid sample slug, in a dispensing position. In the aspiration position, the respective sample paths are out of fluid communication with the dispensing source and, in the dispensing position, the respective sample paths are out of fluid communication with the aspiration source.
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Citations
12 Claims
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1. A manifold device for use with a valve assembly, an aspiration source and a dispensing source to transfer fluid from at least one of a plurality of fluid reservoirs to at least one test site on a substrate surface, said valve assembly including a rotor face defining a plurality of discrete communication channels each movable as a unit between an aspiration condition and a dispensing condition as the valve assembly rotates relative its rotational axis, said manifold device comprising:
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a manifold body defining a plurality of fluid aspiration conduits each having a first aspiration port in fluid communication with the aspiration source, and a second aspiration port in selective fluid communication with a corresponding communication channel of the valve assembly to aspirate a respective liquid sample slug from a corresponding reservoir of sample fluid into discrete sample paths when the valve assembly is in the aspiration condition, said manifold body further defining a plurality of fluid dispensing conduits each having a respective first dispensing port in fluid communication with the dispensing source, and a second dispensing port in selective fluid communication with a corresponding communication channel of the valve assembly to selectively dispense at least one droplet of the corresponding liquid sample slug from the corresponding sample path when the valve assembly is in the dispensing condition, wherein, in the aspiration condition, said respective sample paths are out of fluid communication with the dispensing source and, in the dispensing condition, said respective sample paths are out of fluid communication with the aspiration source. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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Specification