Method for determining an analyte in a fluid
First Claim
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1. A method for determining analyte concentration in a fluid sample, the method comprising the acts of:
- (a) providing a test strip having a sample side and a reaction side, the test strip including a porous membrane, the test strip being adapted to accept a sample on the sample side and pass it towards the reaction side, said test strip including a testing reagent, said testing reagent comprising a color-indicator system that changes color to indicate the presence of the analyte in the sample, said test strip further having a polymer on at least the reaction side, said polymer increasing the opacity of at least a portion of the test strip after contact with a sample, said polymer being selected from the group consisting of acrylic latex polymers, polystyrene sodium sulfate polymers, and combinations thereof;
(b) applying the sample to the sample side of the test strip; and
(c) determining the analyte concentration of the sample using information from the color indicator system.
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Abstract
A reagent strip for measuring the concentration of glucose in whole blood has a polymer on at least one side thereof to increase the opacity thereof, thereby reducing the effect of hematocrit on the glucose determination.
27 Citations
12 Claims
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1. A method for determining analyte concentration in a fluid sample, the method comprising the acts of:
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(a) providing a test strip having a sample side and a reaction side, the test strip including a porous membrane, the test strip being adapted to accept a sample on the sample side and pass it towards the reaction side, said test strip including a testing reagent, said testing reagent comprising a color-indicator system that changes color to indicate the presence of the analyte in the sample, said test strip further having a polymer on at least the reaction side, said polymer increasing the opacity of at least a portion of the test strip after contact with a sample, said polymer being selected from the group consisting of acrylic latex polymers, polystyrene sodium sulfate polymers, and combinations thereof; (b) applying the sample to the sample side of the test strip; and (c) determining the analyte concentration of the sample using information from the color indicator system. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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Specification