DUAL ELECTRODE SYSTEM FOR A CONTINUOUS ANALYTE SENSOR
First Claim
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1. An continuous glucose monitoring system configured for measuring glucose in a host, the system comprising:
- a continuous glucose sensor comprising;
a first working electrode configured to generate a first signal indicative of glucose and non-glucose related electroactive compounds having a first oxidation potential; and
a second working electrode configured to generate a second signal indicative of non-glucose related electroactive compounds having the first oxidation potential; and
electronics configured to process the first signal and the second signal;
wherein the sensor further comprises at least two mechanisms configured to substantially block or substantially eliminate noise in the sensor signal, the mechanisms comprising a first mechanism disposed on the sensor and configured to reduce or substantially block interferants from reaching the first working electrode and the second working electrode, and a second mechanism in the electronics comprising programming configured to process the first signal to substantially eliminate a signal associated with the non-glucose related electroactive compounds therefrom.
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Abstract
Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure analyte or non-analyte related signal, both of which electrode include an interference domain.
964 Citations
11 Claims
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1. An continuous glucose monitoring system configured for measuring glucose in a host, the system comprising:
a continuous glucose sensor comprising; a first working electrode configured to generate a first signal indicative of glucose and non-glucose related electroactive compounds having a first oxidation potential; and a second working electrode configured to generate a second signal indicative of non-glucose related electroactive compounds having the first oxidation potential; and electronics configured to process the first signal and the second signal; wherein the sensor further comprises at least two mechanisms configured to substantially block or substantially eliminate noise in the sensor signal, the mechanisms comprising a first mechanism disposed on the sensor and configured to reduce or substantially block interferants from reaching the first working electrode and the second working electrode, and a second mechanism in the electronics comprising programming configured to process the first signal to substantially eliminate a signal associated with the non-glucose related electroactive compounds therefrom. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A method for providing a substantially noise-free signal for a glucose sensor implanted in a host, the method comprising:
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implanting a glucose sensor in a host, the glucose sensor comprising;
a first working electrode disposed beneath an active enzymatic portion of a sensor membrane;and a second working electrode disposed beneath an inactive-enzymatic or a non-enzymatic portion of a sensor membrane, wherein the sensor is configured to substantially block one or more interferants from reaching the first working electrode and the second working electrode; generating a first signal indicative of glucose and non-glucose related electroactive compounds having a first oxidation potential; generating a second signal indicative of non-glucose related electroactive compounds having the first oxidation potential; and processing the first signal to substantially eliminate the signal associated with the non-glucose related electroactive compounds therefrom.
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Specification