Monitoring Intraocular Pressure

• US 20090076367A1
• Filed: 11/17/2008
• Published: 03/19/2009
• Est. Priority Date: 05/17/2006
• Status: Abandoned Application

• Current Assignee: Mayo Foundation For Medical Education And Research (Mayo Clinic)
• Original Assignee: Mayo Foundation For Medical Education And Research (Mayo Clinic)
• Inventors: Sit, Arthur J., McLaren, Jay W.
• Application Number:
  US12/272,180
• Publication Number:
  US 20090076367A1
• Time in Patent Office: Days
• US Class Current: 600/398
• CPC Class Codes: A61B 3/16 for measuring intraocular pressure, e.g. tonometers

Abstract

Some embodiments of the system described herein provide non-invasive intraocular pressure monitoring throughout an extended period. Such monitoring systems can be used for the diagnosis and management of glaucoma patients and those at risk for glaucoma. In some embodiments, the monitoring system provides intraocular pressure monitoring in the patient'"'"'s normal environment without the need to house the patient in a sleep laboratory.

Claims

1. An intraocular pressure monitoring system, comprising:

a contact lens device that is removably engageable with an eye, the contact lens device including a sensor device to detect when a deformable portion of the contact lens device is indented by a predetermined amount;

a headset device that applies a force to indent the deformable portion of the contact lens device, the headset device including at least one force sensor coupled to a headset frame; and

a control system to activate the headset device to apply the force on the contact lens device, the control system being in electrical communication with the force sensor to record data from the force sensor when the contact lens device is indented by the predetermined amount.

2. The system of claim 1, wherein the at least one force sensor of the headset device provides data while the contact lens device operates free of a force sensor.

3. The system of claim 1, wherein the contact lens device comprises a magnet in the deformable portion, the deformable portion having no force sensor embedded therein.

4. The system of claim 1, wherein the headset device is activated to apply the force on the contact lens device at a regular interval over an extended period of time.

5. The system of claim 4, wherein the headset device is activated to apply the force on the contact lens device at the regular interval selected from the group consisting of every five minutes, every ten minutes, every twenty minutes, and every sixty minutes.

6. The system of claim 4, wherein the headset device is activated to apply the force on the contact lens device over the extended period of time selected from the group consisting of six hours, twelve hours, and twenty-four hours.

7. The system of claim 1, wherein the control system records data to monitor the intraocular pressure both when the eye is opened and when the eye is closed.

8. The system of claim 7, wherein the contact lens device and the headset device are wearable by a sleeping user so that the control system collects data when the user is in a nocturnal phase.

9. The system of claim 8, wherein the control system collects data from the force sensor of the headset device to generate an intraocular pressure profile recorded over at least a 24-hour period.

10. The system of claim 1, wherein the headset device and contact lens device cooperate to passively measure a force without manual activation by the user.

11. The system of claim 1, wherein the headset device interacts with the contact lens device to provide a nonsurgical system to monitor intraocular pressure.

12. The system of claim 1, wherein the deformable portion of the contact lens device is at least partially displaced in response to a magnetic field generated from the headset device.

13. The system of claim 12, wherein contact lens device includes a magnet attached to the deformable portion.

14. The system of claim 13, wherein the contact lens device further comprises an RFID tag and an antenna line to connect with the RFID tag.

15. The system of claim 14, wherein the sensor device of the contact lens device comprises a break in the antenna line formed when the deformable portion is indented by the predetermined amount.

16. The system of claim 14, wherein the deformable portion is at least partially defined by a groove formed in contact lens material.

17. The system of claim 16, wherein the sensor device of the contact lens device comprises conductive contact elements in communication with the antenna line, the conductive contact elements being separated across the groove when the deformable portion is indented by the predetermined amount.

18. The system of claim 1, wherein the headset device comprises at least one induction coil coupled to the frame.

19. The system of claim 18, wherein the induction coil of the headset device generates a magnetic field that acts upon a magnet of the contact lens device.

20. The system of claim 18, wherein the headset device comprises a pair of induction coils coupled to the frame, the system further comprising a second contact lens device that is removably engageable with a second eye such that the pair of induction coils are positionable proximate to the first and second contact lens devices.

21. The system of claim 1, wherein the headset frame comprises a wearable frame for eyeglasses.

22. The system of claim 21, wherein at least a portion of the control system is housed by the wearable frame.

23. The system of claim 1, wherein at least a portion of the control system is wearable by a user.

24. The system of claim 1, wherein the control system includes a controller circuit to selectively activate the headset device, a rechargeable battery that provides electrical power to the headset device, and a memory module to record data from the force sensor.

25. A contact lens device for use in an intraocular pressure monitoring system, the contact lens device comprising:

a soft contact material that is removably engageable with an eye;

a magnet attached to a deformable portion of the soft contact material;

a RFID device to communicate a code when activated, the RFID device being attached to the soft contact material;

an antenna line to wirelessly communicate the code provided by the RFID device, the antenna line being attached to the soft contact material; and

a switch device to indicate when the deformable portion of the contact lens device is displaced by a predetermined amount.

26. The contact lens device of claim 25, wherein the switch device cuts off at least a portion of the antenna line from the RFID device when the deformable portion is displaced by the predetermined amount.

27. The contact lens device of claim 26, wherein the switch device comprises a break in the antenna line formed when the deformable portion is displaced by the predetermined amount.

28. The contact lens device of claim 26, wherein the deformable portion is at least partially defined by a groove formed in contact lens material.

29. The contact lens device of claim 28, wherein the sensor device of the contact lens device comprises conductive contact elements in communication with the antenna line, the conductive contact elements being separated across the groove when the deformable portion is displaced by the predetermined amount.

30. The contact lens device of claim 25, wherein the deformable portion of the contact lens device is at least partially displaced in response to a magnetic field generated from an external source.

31. The contact lens device of claim 30, wherein the RFID device comprises an RFID tag to output a code to an RFID reader arranged external to the contact lens device.

32. The contact lens device of claim 31, wherein the antenna communicates the code from the RFID tag in response to a magnetic field while the contact lens device operates free of a force sensor.

33. The contact lens device of claim 32, wherein the antenna communicates the code from the RFID tag both when the eye is opened and when the eye is closed.

34. The contact lens device of claim 33, wherein the contact lens device is wearable by a sleeping user so that the antenna communicates the code from the RFID tag when the user is in a nocturnal phase.

35. A headset device for use in an intraocular pressure monitoring system, the headset device comprising:

a frame that is wearable on a head of a user;

at least one induction coil coupled to the frame so that the induction coil is arranged proximate an eye when the frame is worn on the head, the induction coil generating a magnetic field to act upon a magnet external to the headset device; and

a force sensor coupled to the frame to detect a force applied to the induction coil.

36. The headset device of claim 35, further comprising a communication line to transmit data from the force sensor to a control system.

37. The headset device of claim 36, wherein at least a portion of the control system is housed by the wearable frame.

38. The headset device of claim 35, wherein the headset device comprises a pair of induction coils coupled to the frame so that the pair of induction coils are arranged proximate a pair of eyes when the frame is worn on the head.

39. The headset device of claim 35, wherein the wearable frame comprises a frame for eyeglasses.

40. A method for monitoring intraocular pressure, comprising

activating at least one induction coil to generate a magnetic field that applies a force to a contact lens device removably engaged with an eye, the induction coil being coupled to a wearable frame of a headset device so that the induction coil is arranged proximate to the eye;

receiving data from a force sensor arranged on the headset device while the magnetic field is being generated by the induction coil;

detecting a change in a wireless signal from the contact lens device;

recording data from the force sensor when the change in the wireless signal is detected.

41. The method of claim 40, further comprising deactivating the induction coil to shut off the magnetic field when the change in the wireless signal is detected.

42. The method of claim 40, further increasing the intensity of the magnetic field generated by the induction coil until the change in the wireless signal is detected.

43. The method of claim 40, repeating the activating operation, the receiving operation, the detecting operation, and the recording operation at a regular interval over an extended period of time.

44. The method of claim 43, wherein the operations are repeated at the regular interval selected from the group consisting of every five minutes, every ten minutes, every twenty minutes, and every sixty minutes.

45. The method of claim 43, wherein the operations are repeated over the extended period of time selected from the group consisting of six hours, twelve hours, and twenty-four hours.

46. The method of claim 43, further comprising collecting data from the force sensor of the headset device to generate an intraocular pressure profile recorded over at least a 24-hour period.

48. The method of claim 43, wherein the operations are repeated over the extended period of time selected from the group consisting of six hours, twelve hours, and twenty-four hours.

49. The method of claim 48, generating an intraocular pressure profile recorded over the extended period of time.

47. A method for monitoring intraocular pressure, comprising

applying a magnetic field from a headset device to magnet coupled with contact lens device removably engaged with an eye, the headset device comprising wearable frame so that the headset device arranged proximate to the eye;

receiving information indicative of a tear film pressure between the contact lens device and a cornea of the eye, the tear film pressure being detected by a pressure sensor coupled with contact lens device while the magnetic field is being applied to the magnet coupled with contact lens device;

storing data indicative of an intraocular pressure based upon the information indicative of the tear film pressure between the contact lens device and the cornea.