Method and System for Achieving Volumetric Accuracy in Hemodialysis Systems

• US 20090076434A1
• Filed: 09/12/2008
• Published: 03/19/2009
• Est. Priority Date: 09/13/2007
• Status: Abandoned Application

• Current Assignee: Fresenius Medical Care Holdings Incorporated (Fresenius Medical Care AG)
• Original Assignee: Fresenius Medical Care Holdings Incorporated (Fresenius Medical Care AG)
• Inventors: Treka, Milan V., Clemens, Cherles E., Mischelevich, David J., Joseph, Russ T., Robinson, Thomas P., Braig, James R., Foster, Clark B., Fulkerson, Barry N.
• Application Number:
  US12/210,080
• Publication Number:
  US 20090076434A1
• Time in Patent Office: Days
• US Class Current: 604/6.110
• CPC Class Codes: A61M 1/3441 Substitution rate control as a function of the ultrafiltration rate
• CPC Class Codes: A61M 1/3486 Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents

Abstract

Volumetric accuracy in hemodialysis systems is provided by swapping pumps between the replacement fluid side and the output side for a hemofiltration system and between the return fluid side and the sorbent side for a closed-loop, sorbent-based system, such that same quantity of fluid is pumped at each point after the end of an even number of pump swaps. A method for calculating the time interval between swaps is provided based on an allowable difference in amount pumped in the two functions at any given time. A mechanism is provided for compensating for the differences in head pressure presented to the pumps for fluid coming from the replacement-fluid containers or the reservoir and that coming back from the patient through the dialyzer. The pump-swapping system provides an accurate means that can be inexpensively implemented, including using a disposable device.

Claims

1. A system for maintaining volumetric balance of the fluid infused into a patient and the fluid removed from said patient during renal dialysis, the system comprising:

a first fluid circuit for infusing fluid into the patient;

a second fluid circuit for removing fluid from the patient;

a first pump configured to alternately operate on said first circuit and said second circuit;

a second pump configured to alternately operate on said second circuit and said first circuit; and

a controller for causing said first pump to alternatively operate on said first circuit and said second circuit and for causing said second pump to alternatively operate on said first circuit and said second circuit, wherein each of the said first pump and second pump operate only one circuit at a given time.

2. The system of claim 1, wherein the first pump delivers a higher amount of fluid per unit time than the second pump.

3. The system of claim 1, wherein said first and second pumps alternately operate on said first and second circuits for a time interval ‘

T’

, wherein ‘

T’

is derived from an allowable difference in the amount of fluid delivered per unit time by the said first and second pumps.

4. The system of claim 1, wherein said first and second pumps are peristaltic pumps.

5. The system of claim 1, wherein the first and second pumps and first and second fluid circuits are implemented in the form of a disposable device.

6. The system of claim 1 further comprising a restrictor for equalizing a pressure differential between said first and second circuits.

7. The system of claim 6 wherein said restrictor is active and equalizes said pressure differential based upon a measured pressure differential derived from a first pressure sensor in said first circuit and from a second pressure sensor in said second first circuit.

8. The system of claim 1, wherein the system is a hemofiltration system.

9. The system of claim 1, wherein the system is a closed-loop, sorbent-based system.

10. A method for maintaining volumetric balance of the fluid infused into a patient and the fluid removed from said patient during renal dialysis, the method comprising:

using a first fluid circuit for infusing fluid into the patient;

using a second fluid circuit for removing fluid from the patient;

providing a first pump having an ability to alternately operate on said first circuit and said second circuit;

providing a second pump having an ability to alternately operate on said second circuit and said first circuit;

causing said first pump to alternatively operate on said first circuit and said second circuit; and

causing said second pump to alternatively operate on said first circuit and said second circuit, wherein each of the said first pump and second pump operate only one circuit at a given time.

11. The method of claim 10, wherein said first pump delivers a higher amount of fluid per unit time than the second pump.

12. The method of claim 10, which includes alternately operating said first and second pumps on said first and second circuits for a time interval ‘

T’

, wherein ‘

T’

is derived from an allowable difference in the amount of fluid delivered per unit time by the said first and second pumps.

13. The method of claim 10, wherein the method is implemented by a disposable device.

14. The method of claim 10 further comprising the step of equalizing a pressure differential between said first and second circuits.

15. The method of claim 10 wherein said pressure differential is determined based upon a measured pressure differential derived from a first pressure sensor in said first circuit and from a second pressure sensor in said second first circuit.

16. A method for maintaining volumetric balance of the fluid infused into a patient and the fluid removed from said patient during renal dialysis, the method comprising:

using a first fluid circuit for infusing fluid into the patient;

using a second fluid circuit for removing fluid from the patient;

providing a first pump having an ability to alternately operate on said first circuit and said second circuit;

providing a second pump having an ability to alternately operate on said second circuit and said first circuit;

causing said first pump to alternatively operate on said first circuit and said second circuit;

causing said second pump to alternatively operate on said first circuit and said second circuit, wherein each of the said first pump and second pump operate only one circuit at a given time; and

equalizing a pressure differential between said first and second circuits, wherein said pressure differential is determined based upon a measured pressure differential derived from a first pressure sensor in said first circuit and from a second pressure sensor in said second first circuit.

17. The method of claim 16, wherein said first pump delivers a higher amount of fluid per unit time than the second pump.

18. The method of claim 16, which includes alternately operating said first and second pumps on said first and second circuits for a time interval ‘

T’

, wherein ‘

T’

is derived from an allowable difference in the amount of fluid delivered per unit time by the said first and second pumps.

19. The method of claim 16, wherein said first and second pumps are peristaltic pumps.

20. The method of claim 16, wherein the method is implemented by a disposable device.