PROSTATE CANCER ABLATION
First Claim
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1. A method of delivering electric fields to a prostate tissue of a patient, comprising:
- positioning a plurality of electrodes in a target tissue region comprising the prostate tissue; and
establishing an electrical current flow radially or in a plurality of different directions through a volume of the prostate tissue so as to preferentially ablate cancerous cells in the volume, the electrical current flow comprising a frequency of less than about 300 kHz.
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Abstract
Methods and systems for delivering electrical energy and controlled, mild hyperthermia to a prostate tissue of a patient for destruction of cancerous and/or hyperplastic tissue. A method includes positioning a plurality of electrodes in a target tissue region comprising the prostate tissue, and establishing an alternating electrical current flow through a volume of the prostate tissue to induce mild heating and destruction of cancerous cells in the volume.
143 Citations
21 Claims
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1. A method of delivering electric fields to a prostate tissue of a patient, comprising:
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positioning a plurality of electrodes in a target tissue region comprising the prostate tissue; and establishing an electrical current flow radially or in a plurality of different directions through a volume of the prostate tissue so as to preferentially ablate cancerous cells in the volume, the electrical current flow comprising a frequency of less than about 300 kHz. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 19)
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15. A system for preferential destruction of cancerous or hyperplastic cells of a prostate tissue of a patient, comprising:
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a plurality of electrodes for advancement and positioning in a target tissue region of the patient comprising prostate tissue; a control system comprising a power source coupled to the electrodes, and a computer readable storage media comprising instructions that, when executed, cause the control system to; provide electrical current to the electrodes so as to establish a current flow radially or in a plurality of different directions through a volume of the prostate tissue and to preferentially destroy cancerous or hyperplastic cells in the target tissue region; maintain an average target tissue temperature of less than about 50 degrees C. during energy delivery. - View Dependent Claims (16, 17, 18, 20, 21)
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Specification