METAL ALLOY FOR A STENT

• US 20090076589A1
• Filed: 11/17/2008
• Published: 03/19/2009
• Est. Priority Date: 03/03/2005
• Status: Active Grant

• Current Assignee: Mirus LLC
• Original Assignee: ICON Interventional Systems, Inc.
• Inventors: Patel., Udayan, Furst, Joseph G., Buckman, Raymond W. JR.
• Granted Patent: US 7,648,590 B2
• Time in Patent Office: Days
• US Class Current: 623/1.150
• CPC Class Codes: A61F 2/82 Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents stent-grafts for tubular structures of the body other than blood vessels A61F2/04; stent-grafts for blood vessels A61F2/07; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95; for closing wounds, or holding wounds closed A61B17/04 - A61B17/115; dilators A61M29/00
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61L 31/022 Metals or alloys
• CPC Class Codes: Y10S 606/907 Composed of particular material or coated

Abstract

A stent that is at least partially formed of a novel metal alloy, which novel metal alloy improves the physical properties of the stent.

Claims

1-50. -50. (canceled)

51. A medical device at least partially formed of a metal alloy which improves the strength and radiopacity of the medical device, said metal alloy including at least about 95 weight percent of a solid solution of rhenium and molybdenum, said metal alloy including 40-55 weight percent rhenium and 45-60 weight percent molybdenum.

52. The medical device as defined in claim 51, wherein said metal alloy has an average yield strength of at least about 95 ksi and an average ultimate tensile strength of at least about 95 ksi, said metal alloy having an average grain size of over 5 ASTM, and said metal alloy having an average tensile elongation of at least about 25%.

53. The medical device as defined in claim 52, wherein said metal alloy includes carbon and oxygen and having a carbon to oxygen atomic ratio of at least about 1:

1.

54. The medical device as defined in claim 53, wherein said metal alloy includes a carbon to nitrogen atomic ratio of less than about 40:

1 and an oxygen to nitrogen atomic ratio of less than about 30;

1.

56. The medical device as defined in claim 51, 52, 53 or 54, wherein said metal alloy including over 99 weight percent of a solid solution.

57. The medical device as defined in claim 51, 52, 53 or 54, wherein said metal alloy including at least about 99.95 weight percent of a solid solution.

58. The medical device as defined in claim 51, wherein said metal alloy including carbon and oxygen and having a carbon to oxygen atomic ratio of less than about 50:

1.

59. The medical device as defined in claim 56, wherein said metal alloy including carbon and oxygen and having a carbon to oxygen atomic ratio of less than about 50:

1.

60. The medical device as defined in claim 57, wherein said metal alloy including carbon and oxygen and having a carbon to oxygen atomic ratio of less than about 50:

1.

61. The medical device as defined in claim 51, wherein said metal alloy has a nitrogen content of less than about 20 ppm, a carbon content of less than about 150 ppm, and an oxygen content of less than about 50 ppm.

62. The medical device as defined in claim 59, wherein said metal alloy has a nitrogen content of less than about 20 ppm, a carbon content of less than about 150 ppm, and an oxygen content of less than about 50 ppm.

63. The medical device as defined in claim 60, wherein said metal alloy has a nitrogen content of less than about 20 ppm, a carbon content of less than about 150 ppm, and an oxygen content of less than about 50 ppm.

64. The medical device as defined in claim 51, wherein said metal alloy has an average density of at least 10 gm/cc.

65. The medical device as defined in claim 62, wherein said metal alloy has an average density of at least 10 gm/cc.

66. The medical device as defined in claim 51, wherein said metal alloy includes about 46-49 weight percent rhenium and about 51-54 weight percent molybdenum.

67. The medical device as defined in claim 65, wherein said metal alloy includes about 46-49 weight percent rhenium and about 51-54 weight percent molybdenum.

68. The medical device as defined in claim 51, wherein said metal alloy includes about 40-55 weight percent rhenium and about 45-60 weight percent molybdenum.

69. The medical device as defined in claim 65, wherein said metal alloy includes about 40-55 weight percent rhenium and about 45-60 weight percent molybdenum.

70. The medical device as defined in claim 56, wherein said metal alloy includes at least about 99.9 weight percent rhenium and molybdenum.

71. The medical device as defined in claim 51, wherein said carbon content of said metal alloy is less than about 100 ppm and said oxygen content of said metal alloy is less than about 50 ppm, and a carbon to oxygen atomic ratio of at least about 1:

1.

72. The medical device as defined in claim 66, 67, 68 or 69, wherein said carbon content of said metal alloy is less than about 100 ppm and said oxygen content of said metal alloy is less than about 50 ppm, and a carbon to oxygen atomic ratio of at least about 1:

1.

73. The medical device as defined in claim 71, wherein said carbon content of said metal alloy is less than about 50 ppm and said oxygen content of said metal alloy is less than about 10 ppm.

74. The medical device as defined in claim 72, wherein said carbon content of said metal alloy is less than about 50 ppm and said oxygen content of said metal alloy is less than about 10 ppm.

75. The medical device as defined in claim 51 wherein said atomic ratio of carbon to oxygen in said metal alloy is less than about 50:

1.

76. The medical device as defined in claim 74, wherein said atomic ratio of carbon to oxygen in said metal alloy is less than about 50:

1.

77. The medical device as defined in claim 51, wherein said metal alloy includes nitrogen, said nitrogen content of said metal alloy is less than about 20 ppm.

78. The medical device as defined in claim 76, wherein said metal alloy includes nitrogen, said nitrogen content of said metal alloy is less than about 20 ppm.

79. The medical device as defined in claim 51, wherein said metal alloy has an average grain size of about 5-10 ASTM.

80. The medical device as defined in claim 78, wherein said metal alloy has an average grain size of about 5-10 ASTM.

81. The medical device as defined in claim 51, wherein said metal alloy constitutes at least about 80 weight percent of said medical device.

82. The medical device as defined in claim 80, wherein said metal alloy constitutes at least about 80 weight percent of said medical device.

83. The medical device as defined in claim 51, wherein said metal alloy comprises by weight percent:

84. The medical device as defined in claim 82, wherein said metal alloy comprises by weight percent:

85. The medical device as defined in claim 51, wherein said metal alloy comprises by weight percent:

86. The medical device as defined in claim 84, wherein said metal alloy comprises by weight percent:

87. The medical device as defined in claim 51, wherein said metal alloy comprises by weight percent:

88. The medical device as defined in claim 86, wherein said metal alloy comprises by weight percent:

55. The medical device as defined in any of the proceeding claims, wherein said medical device is a stent, graft, valve, screw, nail, rod, PFO device, prosthetic device, sheath, guide wire, balloon catheter, hypotube, catheter, electrophysiology catheter, staple or cutting device.

89. A stent that is formed of at least about 80 weight percent of a metal alloy which improves the strength and ductility of the stent, said metal alloy including at least about 99.9 weight percent of a solid solution of rhenium and molybdenum, said metal alloy including carbon and oxygen and having a carbon to oxygen atomic ratio of at least about 1:

1 and less than about 50;

1, said metal alloy having a carbon to nitrogen atomic ratio of less than about 40;

1 and an oxygen to nitrogen atomic ratio of less than about 30;

1, said metal alloy having an average yield strength of about 98-122 ksi and an average ultimate tensile strength of about 100-150 ksi, said metal alloy having an average grain size of about 6-9 ASTM, said metal alloy having an average tensile elongation of about 25-35%, and including by weight percent;

90. The stent as defined in claim 89, wherein said metal alloy comprises by weight percent: