METHOD AND DEVICE AND PREDICTING PHYSIOLOGICAL VALUES
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Abstract
The invention relates generally to methods, systems, and devices for measuring the concentration of target analytes present in a biological system using a series of measurements obtained from a monitoring system and a Mixtures of Experts (MOE) algorithm. In one embodiment, the present invention describes a method for measuring blood glucose in a subject.
21 Citations
34 Claims
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1-24. -24. (canceled)
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25. A method for measuring an amount or concentration of analyte present in a biological system, said method comprising:
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determining a measurement value indicative of the amount or concentration of analyte present in the biological system; providing two or more ranges of measurement values; identifying the range in which said determined measurement value falls; employing an algorithm for prediction of further measurement values wherein said algorithm is optimized for performance in the identified range; and generating further measurement values indicative of amount or concentration of analyte present in the biological system using said algorithm - View Dependent Claims (26, 27, 28, 29, 30, 31, 32)
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33. The method of claim 44, wherein said calibration step provides a calibrated signal by a method compromising
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( active ) wherein, signal is the calibrated signal, BGcp is blood glucose value at a calibration point, activecp is an active signal that corresponds to an electrochemical sensor signal at the calibration point, and active is an active signal that corresponds to an electrochemical sensor signal.
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34. The method of claim 44, wherein said calibration step provides a calibrated signal by a method comprising
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( active + offset ) wherein, signal is the calibrated, signal, BGcp is blood glucose value at a calibration point, activecp is an active signal that corresponds to an electrochemical sensor signal at the calibration point, active is an active signal that corresponds to an electrochemical sensor signal, and offset is a value that takes into account a non-zero y-intercept value.
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Specification