Compositions and Methods for Enhancing In-Vivo Uptake of Pharmaceutical Agents
First Claim
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1. A pharmaceutical composition comprising:
- (a) at least one pharmaceutical agent as an active ingredient;
(b) nanostructures and liquid, wherein said nanostructures comprise a core material of a nanometric size enveloped by ordered fluid molecules of said liquid, said core material and said envelope of ordered fluid molecules being in a steady physical state and whereas said nanostructures and liquid being formulated to enhance in vivo uptake of said at least one pharmaceutical agent.
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Abstract
Pharmaceutical compositions comprising liquid, nanostructures and pharmaceutical agents are provided. Methods of use such compositions are also provided.
82 Citations
41 Claims
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1. A pharmaceutical composition comprising:
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(a) at least one pharmaceutical agent as an active ingredient; (b) nanostructures and liquid, wherein said nanostructures comprise a core material of a nanometric size enveloped by ordered fluid molecules of said liquid, said core material and said envelope of ordered fluid molecules being in a steady physical state and whereas said nanostructures and liquid being formulated to enhance in vivo uptake of said at least one pharmaceutical agent. - View Dependent Claims (3, 6, 28, 29, 31, 32)
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- 2. A method of enhancing in vivo uptake of a pharmaceutical agent into a cell comprising administering to an individual the pharmaceutical agent in combination with nanostructures and liquid, wherein said nanostructures comprise a core material of a nanometric size enveloped by ordered fluid molecules of said liquid, said core material and said envelope of ordered fluid molecules being in a steady physical state and whereas said nanostructures and liquid being formulated to enhance in vivo uptake the pharmaceutical agent, thereby enhancing in vivo uptake of the pharmaceutical agent into the cell.
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4-5. -5. (canceled)
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7-27. -27. (canceled)
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30. (canceled)
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33. (canceled)
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40. A pharmaceutical composition comprising:
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(a) taxol as an active ingredient; and (b) nanostructures and liquid, wherein said nanostructures comprise a core material of a nanometric size enveloped by ordered fluid molecules of said liquid, said core material and said envelope of ordered fluid molecules being in a steady physical state. - View Dependent Claims (41)
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Specification