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REACTIVE SURFACE ON A POLYMERIC SUBSTRATE

  • US 20090081797A1
  • Filed: 08/29/2008
  • Published: 03/26/2009
  • Est. Priority Date: 08/31/2007
  • Status: Abandoned Application
First Claim
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1. A method for making a polymer substrate having a working surface upon which biologically active compounds can bind comprising:

  • providing a cyclic polyolefin copolymer;

    treating the cyclic polyolefin copolymer with plasma to provide functional groups on a surface of the polymer substrate;

    exposing the plasma-treated copolymer to a conjugate so that the functional groups on the surface of the polymer substrate form covalent bonds with the conjugate;

    exposing the polymer surface covalently bound to the conjugate to a biologically active compound so that the biologically active compound is immobilized on the polymer surface.

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