METHOD OF ENHANCING IONTOPHORETIC DELIVERY OF A PEPTIDE
First Claim
1. A method of transdermally administering a peptide to a patient comprising microporating the skin of the patient with a microneedle while concurrently administering the peptide through the microneedle using iontophoresis.
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Abstract
The present invention provides methods for the administration of a peptide to a body surface of the patient comprising treating said body surface by microporation and iontophoretically administering the peptide to the body surface. The present invention also encompasses a method of transdermally administering a peptide to the skin of a patient comprising treating the skin with microporation and iontophoretically administering said peptide to the skin. In one embodiment, the body surface or skin is microporated using one or more microneedles.
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Citations
32 Claims
- 1. A method of transdermally administering a peptide to a patient comprising microporating the skin of the patient with a microneedle while concurrently administering the peptide through the microneedle using iontophoresis.
- 24. A method of transdermally administering a peptide to a patient comprising pretreating the patient'"'"'s skin with microporation using a microneedle followed by administration of said peptide using iontophoresis.
Specification