NANOELECTRONIC ELECTROCHEMICAL TEST DEVICE
First Claim
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1. A method of immobilizing a biomolecule for sensing a target species on a substrate to fabricate a nanosensor device for sensing the target species, said method comprising:
- providing a plurality of carbon nanotubes and a quantity of a biomolecule configured to interact with the target species in an aqueous solution;
dispersing the plurality of nanotubes and at least some of the quantity of the biomolecule to thereby create a stable suspension of nanotubes and biomolecules in the aqueous solution;
providing a substrate surface having an electrode surface thereon; and
simultaneously depositing nanotubes and biomolecules from the stable suspension to at least the electrode surface to thereby immobilize the biomolecules on the substrate.
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Abstract
Nanoelectronic devices for the detection and quantification of biomolecules are Provided. In certain embodiments, the devices are configured to detect and measure blood glucose levels. Also provided are methods of fabricating nanoelectronic devices for the detection of biomolecules.
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Citations
23 Claims
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1. A method of immobilizing a biomolecule for sensing a target species on a substrate to fabricate a nanosensor device for sensing the target species, said method comprising:
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providing a plurality of carbon nanotubes and a quantity of a biomolecule configured to interact with the target species in an aqueous solution; dispersing the plurality of nanotubes and at least some of the quantity of the biomolecule to thereby create a stable suspension of nanotubes and biomolecules in the aqueous solution; providing a substrate surface having an electrode surface thereon; and simultaneously depositing nanotubes and biomolecules from the stable suspension to at least the electrode surface to thereby immobilize the biomolecules on the substrate. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. A nanoelectronic sensor for glucose detection comprising:
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a non-conductive substrate; a counter electrode and working electrode on said substrate, said working electrode comprising a carbon conductive path and having a surface comprising a carbon nanotube network; a glucose-selective redox enzyme and a mediator in contact with said carbon nanotube network; a sample well configured for receiving a sample and contacting said sample with the glucose-selective redox enzyme. - View Dependent Claims (21, 22, 23)
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Specification