Stable, non-aqueous, single-phase gels and formulations thereof for delivery from an implantable device
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Accused Products
Abstract
The present invention provides a suspension vehicle and suspension formulations deliverable from an implantable delivery device. In particular, the suspension vehicle of the present invention allows the formulation of beneficial agent suspensions that are stable over time at ambient and physiological temperatures. In addition, the beneficial agent suspensions formed using the suspension vehicle of the present invention allow controlled delivery of beneficial agent from an implanted delivery device over sustained periods of time, even when such delivery occurs at low flow rates, through a small-diameter delivery channel. Also included in the present invention are implantable delivery devices.
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Citations
51 Claims
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1-40. -40. (canceled)
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41. A pharmaceutical composition comprising:
a particle formulation comprising a protein, sucrose, methionine, and citrate, wherein the ratio of protein to sucrose to methionine to citrate is substantially 1;
2;
1;
1.7.- View Dependent Claims (42, 43, 44, 45, 46, 47, 48, 49, 50, 51)
Specification