MULTICOMPONENT PROTEIN MICROARRAYS
First Claim
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1. A microarray comprising one or more spots of a biomolecule-compatible matrix having two or more components of a protein-based system entrapped therein, wherein the one or more spots are adhered to a surface.
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Abstract
The present invention involves a multicomponent protein microarray comprising two or more components of a protein-based system entrapped within spots of a biomolecule compatible matrix arranged on a surface. Also included are methods of using the microarray for multicomponent analysis along with kits and machinery comprising the microarray.
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Citations
29 Claims
- 1. A microarray comprising one or more spots of a biomolecule-compatible matrix having two or more components of a protein-based system entrapped therein, wherein the one or more spots are adhered to a surface.
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22. A method of preparing a microarray comprising:
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(a) combining two or more components of a protein-based system with one or more biomolecule-compatible precursor solutions; and (b) applying the combination of (a) to a surface in a microarray format. - View Dependent Claims (23, 24)
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25. A method of performing multi-component assays comprising:
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(a) obtaining a biomolecule compatible microarray comprising a matrix having two or more components of a protein-based system entrapped therein; (b) exposing the biomolecule-compatible microarray to one or more test substances; and (c) detecting a change in the protein-based system. - View Dependent Claims (26)
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Specification