INTRAOCULAR IONTOPHORETIC DEVICE AND ASSOCIATED METHODS
First Claim
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1. A device for delivering an active agent to an eye of a subject, comprising:
- an ocular lens-shaped housing configured to contact a surface of the eye; and
a reservoir coupled to the housing and configured to deliver an active agent to the eye, wherein the reservoir is located entirely within a 180 degree section of the housing.
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Abstract
The present invention includes methods and devices for non-invasively delivering an active agent to the eye of a subject. In one aspect, for example, a device for delivering an active agent to an eye of a subject may include an ocular lens-shaped housing configured to contact a surface of the eye, and a reservoir coupled to the housing and configured to deliver an active agent to the eye, wherein the reservoir is located entirely within a 180 degree section of the housing. In another aspect, the reservoir is located entirely within a 150 degree section of the housing.
67 Citations
25 Claims
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1. A device for delivering an active agent to an eye of a subject, comprising:
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an ocular lens-shaped housing configured to contact a surface of the eye; and a reservoir coupled to the housing and configured to deliver an active agent to the eye, wherein the reservoir is located entirely within a 180 degree section of the housing. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 20, 21)
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14. A method for enhancing ocular delivery of an active agent to the eye of a subject, comprising:
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contacting an ocular lens-shaped housing having a reservoir containing the active agent against an eye surface such that the reservoir contacts a delivery region of the eye, wherein said reservoir is located entirely within a 180 degree section of the housing; and delivering the active agent from the reservoir into the eye while substantially maintaining alignment between the reservoir and the delivery region. - View Dependent Claims (15, 16, 17, 18, 19)
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22. A device for delivering an active agent to an eye of a subject, comprising:
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an ocular lens-shaped housing configured to contact a surface of the eye; and a reservoir coupled to the housing and configured to deliver an active agent to the eye, wherein the reservoir surface area configured to face the eye is less than about 50% of the surface area of the housing configured to face the eye. - View Dependent Claims (23, 24, 25)
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Specification