Systems and methods for correlating past epigenetic information with past disability data

• US 20090094282A1
• Filed: 12/31/2007
• Published: 04/09/2009
• Est. Priority Date: 10/04/2007
• Status: Abandoned Application

• Current Assignee: Searete LLC (Intellectual Ventures LLC)
• Original Assignee: Searete LLC (Intellectual Ventures LLC)
• Inventors: Jung, Edward K.Y., Wood, Lowell L. JR., Rivet, Dennis J., Hyde, Roderick A., Kare, Jordin T., Leuthardt, Eric C.
• Application Number:
  US12/006,249
• Publication Number:
  US 20090094282A1
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: G16H 50/70 for mining of medical data, e.g. analysing previous cases of other patients
• CPC Class Codes: G16Z 99/00 Subject matter not provided for in other main groups of this subclass

Abstract

A method includes receiving epigenetic information associated with at least a first individual for at least a first epigenetic-information interval of time, receiving disability data associated with at least a first individual for at least a first disability-data interval of time, and/or correlating the epigenetic information associated with at least a first individual for at least a first epigenetic-information interval of time with the disability data associated with at least a first individual for at least a first disability-data interval of time.

A system includes means for receiving epigenetic information associated with at least a first individual for at least a first epigenetic-information interval of time, means for receiving disability data associated with at least a first individual for at least a first disability-data interval of time, and means for correlating the epigenetic information associated with at least a first individual for at least a first epigenetic-information interval of time with the disability data associated with at least a first individual for at least a first disability-data interval of time.

Claims

1. A computer-implemented method comprising:

receiving epigenetic information associated with at least a first individual for at least a first epigenetic-information interval of time;

receiving disability data associated with at least a first individual for at least a first disability-data interval of time; and

correlating the epigenetic information associated with at least a first individual for at least a first epigenetic-information interval of time with the disability data associated with at least a first individual for at least a first disability-data interval of time.

2-36. -36. (canceled)

37. A system, comprising:

means for receiving epigenetic information associated with at least a first individual for at least a first epigenetic-information interval of time;

means for receiving disability data associated with at least a first individual for at least a first disability-data interval of time; and

means for correlating the epigenetic information associated with at least a first individual for at least a first epigenetic-information interval of time with the disability data associated with at least a first individual for at least a first disability-data interval of time.

38. The system of claim 37, wherein means for receiving epigenetic information associated with at least a first individual for at least a first epigenetic-information interval of time comprises:

means for receiving the epigenetic information for the at least a first individual and at least a second individual.

39. The system of claim 37, wherein means for receiving epigenetic information associated with at least a first individual for at least a first epigenetic-information interval of time comprises:

means for receiving the epigenetic information in the form of a database.

40. The system of claim 37, wherein means for receiving epigenetic information associated with at least a first individual for at least a first epigenetic-information interval of time comprises:

means for receiving the epigenetic information including a cytosine methylation status of CpG positions.

41. The system of claim 37, wherein means for receiving epigenetic information associated with at least a first individual for at least a first epigenetic-information interval of time comprises:

means for receiving the epigenetic information including histone modification status.

42. The system of claim 37, wherein means for receiving epigenetic information associated with at least a first individual for at least a first epigenetic-information interval of time comprises:

means for receiving the epigenetic information on a subscription basis.

43. The system of claim 37, wherein means for receiving epigenetic information associated with at least a first individual for at least a first epigenetic-information interval of time comprises:

means for receiving anonymized epigenetic information.

44. The system of claim 37, wherein means for receiving epigenetic information associated with at least a first individual for at least a first epigenetic-information interval of time comprises:

means for receiving a first set of epigenetic information; and

means for receiving a second set of epigenetic information.

45. The system of claim 44, further comprising:

means for receiving a third set of epigenetic information.

46. The system of claim 37, wherein means for receiving disability data associated with at least a first individual for at least a first disability-data interval of time comprises:

means for receiving the disability data for at least a second individual for at least a second disability-data interval of time.

47. The system of claim 37, wherein means for receiving disability data associated with at least a first individual for at least a first disability-data interval of time comprises:

means for receiving disability data progression.

48. The computer-implemented method of claim 47, wherein means for receiving disability data progression comprises:

receiving data associated with at least one of lung capacity, histology data, tumor size, tumor growth, body weight, blood cell count, prostate specific antigen, blood glucose levels, insulin levels, cholesterol levels, blood pressure, an electrocardiogram, a stress test, or magnetic resonance imaging tests.

49. The system of claim 37, wherein means for receiving disability data associated with at least a first individual for at least a first disability-data interval of time comprises:

means for receiving at least one of disease data or illness data.

50. The system of claim 49, wherein means for receiving at least one of disease data or illness data comprises:

means for receiving data including at least one of a disease characteristic or a disease symptom.

51. The system of claim 50, wherein means for receiving data including at least one of a disease characteristic or a disease symptom comprises:

means for receiving data indicating at least one of a disease progression state or a diagnosis.

52. The system of claim 37, wherein means for receiving disability data associated with at least a first individual for at least a first disability-data interval of time comprises:

means for receiving data including at least one physical disability.

53. The system of claim 37, wherein means for receiving disability data associated with at least a first individual for at least a first disability-data interval of time comprises:

means for receiving data including at least one mental disability.

54. The system of claim 37, wherein means for receiving disability data associated with at least a first individual for at least a first disability-data interval of time comprises:

means for receiving data including at least one emotional disability.

55. The system of claim 37, wherein means for receiving disability data associated with at least a first individual for at least a first disability-data interval of time comprises:

means for receiving data including at least one late emerging genetic effect.

56. The system of claim 37, wherein means for receiving disability data associated with at least a first individual for at least a first disability-data interval of time comprises:

means for receiving disability data on a subscription basis.

57. The system of claim 37, wherein means for receiving disability data associated with at least a first individual for at least a first disability-data interval of time comprises:

means for receiving disability data in the form of a database.

58. The system of claim 37, wherein means for receiving disability data associated with at least a first individual for at least a first disability-data interval of time comprises:

means for receiving anonymized disability data.

59. The system of claim 37, wherein means for correlating the epigenetic information associated with at least a first individual for at least a first epigenetic-information interval of time with the disability data associated with at least a first individual for at least a first disability-data interval of time comprises:

means for tracking at least one change in an epigenetic profile associated with the at least a first individual;

means for tracking at least one change in a disability data profile associated with the at least a first individual; and

means for correlating the at least one change in the epigenetic profile associated with the at least a first individual with the at least one change in the disability data profile associated with the at least a first individual.

60. The system of claim 59, wherein means for tracking at least one change in an epigenetic profile associated with the at least a first individual comprises:

means for compiling epigenetic information associated with at least a first individual for at least a first epigenetic-information interval of time until the at least a first individual is deceased.

61. The system of claim 60, wherein means for compiling epigenetic information associated with at least a first individual for at least a first epigenetic-information interval of time until the at least a first individual is deceased comprises:

means for compiling epigenetic information associated with at least a second individual until the at least a second individual is deceased for at least a second epigenetic-information interval of time.

62. The system of claim 59, wherein means for tracking at least one change in a disability data profile associated with the at least a first individual comprises:

means for compiling disability data associated with at least a first individual for at least a first disability-data interval of time until the at least first individual is deceased.

63. The system of claim 62, wherein means for compiling disability data associated with at least a first individual for at least a first disability-data interval of time until the at least first individual is deceased comprises:

means for compiling disability data for at least a second individual until the at least a second individual is deceased for at least a second disability-data interval of time.

64. The system of claim 59, wherein means for correlating the at least one change in the epigenetic profile associated with the at least a first individual with the at least one change in the disability data profile associated with the at least a first individual comprises:

means for determining a statistical correlation between at least one aspect of the epigenetic profile and the disability data profile.

65. The system of claim 64, wherein means for determining a statistical correlation between at least one aspect of the epigenetic profile and the disability data profile comprises:

means for determining a statistical correlation between at least one aspect of the epigenetic profile and the disability data profile for the at least a first individual and at least a second individual.

66. The system of claim 64, wherein means for determining a statistical correlation between at least one aspect of the epigenetic profile and the disability data profile comprises:

means for utilizing at least one of a linear correlation, a non-linear correlation, a functional dependency, or another mathematical relationship.

67. The system of claim 64, wherein means for determining a statistical correlation between at least one aspect of the epigenetic profile and the disability data profile comprises:

means for counting at least one occurrence of at least one clinical outcome.

68. The system of claim 37, further comprising:

means for providing to a third party correlated information including the epigenetic information associated with at least a first individual for at least a first epigenetic-information interval of time and the disability data associated with at least a first individual for at least a first disability-data interval of time.

69. The system of claim 68, wherein means for providing to a third party correlated information including the epigenetic information associated with at least a first individual for at least a first epigenetic-information interval of time and the disability data associated with at least a first individual for at least a first disability-data interval of time comprises:

means for providing the correlated information to at least one of an insurer or a legal professional.

70. The system of claim 68, wherein means for providing to a third party correlated information including the epigenetic information associated with at least a first individual for at least a first epigenetic-information interval of time and the disability data associated with at least a first individual for at least a first disability-data interval of time comprises:

means for providing the correlated information to at least one of a health agency or a medical professional.

71. The system of claim 68, wherein means for providing to a third party correlated information including the epigenetic information associated with at least a first individual for at least a first epigenetic-information interval of time and the disability data associated with at least a first individual for at least a first disability-data interval of time comprises:

means for providing the correlated information to an academic institution.

72. The system of claim 68, wherein means for providing to a third party correlated information including the epigenetic information associated with at least a first individual for at least a first epigenetic-information interval of time and the disability data associated with at least a first individual for at least a first disability-data interval of time comprises:

means for providing the correlated information to at least one of the first individual or a second individual.

73. A system, comprising:

circuitry for receiving epigenetic information associated with at least a first individual for at least a first epigenetic-information interval of time;