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PROCESS FOR MAKING MICRONEEDLES, MICRONEEDLE ARRAYS, MASTERS, AND REPLICATION TOOLS

  • US 20090099537A1
  • Filed: 03/23/2007
  • Published: 04/16/2009
  • Est. Priority Date: 03/24/2006
  • Status: Active Grant
First Claim
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1. A process for preparing microneedles comprising(a) providing a photoreactive composition, said photoreactive composition comprising(1) at least one reactive species that is capable of undergoing an acid- or radical-initiated chemical reaction, and(2) at least one multiphoton photoinitiator system;

  • and(b) imagewise exposing at least a portion of said composition to light sufficient to cause simultaneous absorption of at least two photons, thereby inducing at least one acid- or radical-initiated chemical reaction where said composition is exposed to the light, said imagewise exposing being carried out in a pattern that is effective to define at least the surface of a plurality of solid microneedles, wherein the outer surface of the microneedles is characterized by at least one concave area.

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