Systems and methods for assessing and treating medical conditions related to the central nervous system and for enhancing cognitive functions
First Claim
1. A device for assessing and enhancing particular cognitive, behavioral, or affective functions in a patient comprising:
- a neurodiagnostic module for identifying an individual'"'"'s brain regions of interest and associated with particular functional, structural, or cognitive abnormalities and measuring the functional activation or structural maps, or corresponding cognitive performance for a particular task (or tasks) or during a resting period;
a computational module identifying the particular brain regions in an individual whose structure, function, or cognitive functions are deviant from their corresponding statistically-established health norms, or from their corresponding statistical norms for cognitively enhanced performance in a particular task;
a brain trait module for determining whether the identified brain regions from said computational module statistically fits within known structural, functional, or cognitive pathophysiology of a particular brain-related disease, or within established norms for enhanced or excellent cognitive or behavioral performance for a particular task;
a treatment module for computing precise individual-based brain and cognitive stimulation parameters needed to stimulate the particular identified brain regions; and
a stimulator module system for distributing, at least non-invasively, energy to stimulate the identified brain regions associated with the particular functional, structural, or cognitive abnormalities.
1 Assignment
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Accused Products
Abstract
Systems and methods for diagnosing and treating various brain-related conditions, and/or for modifying at least one of cognitive, behavioral, or affective functions or skills in individuals. The method of diagnosing and treating a brain-related condition includes the steps of: (i) identifying at least a brain region associated with the brain-related condition; (ii) stimulating the brain region by employing at least one electrical, magnetic, electromagnetic, and photoelectric stimulus; (iii) optionally, stimulating at least one cognitive feature associated with the brain region; and (iv) optionally, subjecting the brain region to a treatment including at least one of cell replacement therapy, cell regenerative therapy and cell growth.
50 Citations
35 Claims
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1. A device for assessing and enhancing particular cognitive, behavioral, or affective functions in a patient comprising:
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a neurodiagnostic module for identifying an individual'"'"'s brain regions of interest and associated with particular functional, structural, or cognitive abnormalities and measuring the functional activation or structural maps, or corresponding cognitive performance for a particular task (or tasks) or during a resting period; a computational module identifying the particular brain regions in an individual whose structure, function, or cognitive functions are deviant from their corresponding statistically-established health norms, or from their corresponding statistical norms for cognitively enhanced performance in a particular task; a brain trait module for determining whether the identified brain regions from said computational module statistically fits within known structural, functional, or cognitive pathophysiology of a particular brain-related disease, or within established norms for enhanced or excellent cognitive or behavioral performance for a particular task; a treatment module for computing precise individual-based brain and cognitive stimulation parameters needed to stimulate the particular identified brain regions; and a stimulator module system for distributing, at least non-invasively, energy to stimulate the identified brain regions associated with the particular functional, structural, or cognitive abnormalities. - View Dependent Claims (2, 3, 4, 5, 6, 7, 10, 11, 12, 13, 14, 15)
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- 8. The device of claim 8, wherein the treatment module further includes a system of analyzers.
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16. A system for assessing patient neuronal functions:
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a neurodiagnostic module for identifying an individual'"'"'s brain regions of interest and measuring the functional activation or structural maps, or corresponding cognitive performance thereof; a computational module identifying a patients deviant brain regions relative to corresponding statistically-established health norms, or from their corresponding statistical norms; a brain trait module for determining whether the identified brain regions from said computational module statistically fits within known structural, functional, or cognitive pathophysiology of a particular brain-related disease, or within established norms for enhanced or excellent cognitive or behavioral performance for a particular task; and a treatment system computing precise individual-based brain and cognitive stimulation parameters needed to stimulate generating at least non-invasively excitatory or inhibitory energy to stimulate the identified brain regions.
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17. A method of assessing and treating cognitive, behavioral, or affective functions in a patient comprising:
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neurodiagnostically identifying an individual'"'"'s brain regions of interest and associated with particular functional, structural, or cognitive abnormalities and measuring the functional activation or structural maps, or corresponding cognitive performance for a particular task (or tasks) or during a resting period; identifying brain regions in an individual whose structure, function, or cognitive functions are deviant from their corresponding statistically-established health norms, or from their corresponding statistical norms for cognitively enhanced performance in a particular task; determining whether the identified brain regions from said computational module statistically fits within known structural, functional, or cognitive pathophysiology of a particular brain-related disease, or within established norms for enhanced or excellent cognitive or behavioral performance for a particular task; computing precise individual-based brain and cognitive stimulation parameters needed to stimulate the particular identified brain regions; and at least non-invasively discharging energy to stimulate the identified brain regions associated with the particular functional, structural, or cognitive abnormalities. A system for assessing patient neuronal functions
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18. A method of assessing and treating cognitive, behavioral, or affective functions in a patient comprising:
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providing imaging devices to assist with identifying a patients deviant brain regions relative to corresponding statistically-established health norms, or from their corresponding statistical norms; determining whether the identified brain regions statistically fits within known structural, functional, or cognitive pathophysiology of a particular brain-related disease, or within established norms for enhanced or excellent cognitive or behavioral performance for a particular task; and a treatment system computing precise individual-based brain and cognitive stimulation parameters needed to stimulate generating at least non-invasively excitatory or inhibitory energy to stimulate the identified brain regions.
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19. A method of treating cognitive impairments, comprising the steps of:
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identifying at least one brain region associated with a cognitive impairment; subjecting the at least one brain region to at least non-invasive excitatory or inhibitory stimulus energy; and simultaneously, modifying a cognitive function associated with the at least one brain region. - View Dependent Claims (20)
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21. A method of therapy for impaired cognitive functions, the method comprising the steps of:
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providing a first stimulus to a pre-defined brain region of an individual without stimulating physically adjacent brain regions, the pre-defined brain region being functionally associated with an impaired cognitive function; and providing at least one cognitive stimulus to the patient, to elicit a response involving the impaired cognitive function. - View Dependent Claims (22, 23)
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24. A method of brain therapy, comprising:
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providing an analyzer system including at least one of a brain analyzer and a cognitive analyzer; the analyzer system measuring at least one property of an individual'"'"'s condition to obtain a measured property related to at least one of at least one brain region and at least one cognitive feature; the analyzer system calculating a norm value from at least one brain region or at least one cognitive feature of healthy or diseased groups of individuals; and the analyzer system comparing the measured property value with the norm value to provide a resultant value. - View Dependent Claims (25)
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26. A method of therapy, comprising:
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measuring a local brain function of at least one brain region to produce a local measurement relative to a norm value of an individual; evaluating the local measurement relative to a normative value of a group of individuals, to produce an evaluation datum; adjusting at least one of one or more non-invasive stimulators and one or more one cognitive stimulators in response to the evaluation datum; and providing stimuli from the at least one or more non-invasive stimulators and the least one or more cognitive stimulators to the at least one brain region. - View Dependent Claims (27, 28)
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29. A method of therapy for a cognitive symptom of a disease, comprising:
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selectively stimulating at least one brain region functionally associated with a cognitive symptom, without physically stimulating adjacent regions; and providing at least one cognitive stimulus selected to elicit a response involving the cognitive symptom. - View Dependent Claims (30, 31, 32, 33, 34)
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35. A method of neuronal therapy comprising:
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providing an analyzer system including at least one of a brain analyzer and a cognitive analyzer; the analyzer measuring at least one property of an individual'"'"'s condition, the measured property being related to at least one of at least one brain region and at least one cognitive feature; the analyzer calculating a norm value from at least one brain region or at least one cognitive feature of healthy or diseased groups of individuals; the analyzer comparing the measured property with the norm value and provide a resultant value; providing a stimulator system including; providing one or more non-invasive stimulators to selectively provide singular or multiple site stimuli to at least one brain region associated with the property; providing one or more cognitive stimulators to selectively provide cognitive stimuli to at least one cognitive function relevant to the at least one property; and providing a controller and interfacing the controller with the analyzer system and the stimulator system, the controller operating at least one of the one or more non-invasive brain stimulators and one or more one cognitive stimulators.
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Specification