Blood Component Measurement Device and Chip for Blood Measurement

• US 20090105613A1
• Filed: 05/16/2006
• Published: 04/23/2009
• Est. Priority Date: 05/16/2005
• Status: Active Grant

• Current Assignee: Terumo Kabushiki Kaisha
• Original Assignee: Terumo Corporation
• Inventors: Nishiuchi, Daisuke
• Granted Patent: US 8,157,749 B2
• Time in Patent Office: Days
• US Class Current: 600/583
• CPC Class Codes: A61B 2562/0295 Strip shaped analyte sensors for apparatus classified in A61B5/145 or A61B5/157 disposable multilayered or laminated electrodes G01N27/307; details of handling chemical test elements G01N33/4875
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/150068 by tissue compression, e.g. with specially designed surface of device contacting the skin area to be pierced
• CPC Class Codes: A61B 5/150358 Strips for collecting blood, e.g. absorbent optical reagent test strips G01N21/8483; chemical reagent test strips G01N33/4875, G01N33/52
• CPC Class Codes: A61B 5/150412 Pointed piercing elements, e.g. needles, lancets for piercing the skin blade-like piercing elements A61B5/150442
• CPC Class Codes: A61B 5/150503 Single-ended needles hollow piercing element tip design A61B5/150396, needle sets for catheters A61M25/06, needles for bringing media into the body A61M5/32
• CPC Class Codes: A61B 5/15111 Semi-automatically triggered, e.g. at the end of the cocking procedure, for instance by biasing the main drive spring or when reaching sufficient contact pressure, the piercing device is automatically triggered without any deliberate action by the user
• CPC Class Codes: A61B 5/15117 comprising biased elements, resilient elements or a spring, e.g. a helical spring, leaf spring, or elastic strap
• CPC Class Codes: A61B 5/1513 comprising linear sliding guides comprising tooth-shaped elements A61B5/15132
• CPC Class Codes: A61B 5/1519 comprising driving means, e.g. a spring, for propelling the piercing unit
• CPC Class Codes: A61B 5/15194 fully automatically retracted, i.e. the retraction does not require a deliberate action by the user, e.g. by terminating the contact with the patient's skin
• CPC Class Codes: A61B 5/157 Devices characterised by integrated means for measuring characteristics of blood

Abstract

A blood component measurement device (10) has a puncturing unit (18) provided inside a housing (12) and having a puncture needle (16); a button unit (20) for advancing and retreating the puncture needle (16); a contact mechanism (68) coming into contact with the skin of a person to be measured; and a holder (14) for displaceably holding the puncturing unit (18). The blood component measurement device (10) also has an introduction section (94) at the substantially center of a contact member (70). After the skin is punctured by the puncture needle (16) provided at the substantially center of the mechanism (68), the introduction section (94) introduces blood to testing paper (100) when the contact member (70) of the contact mechanism (68) is displaced in a sliding manner along a guide member (72).

Claims

1. A blood component measurement device comprising;

a tip for blood measurement comprising a puncture needle possessing an axis and movable for being advanced and retreated in an axial direction of the needle;

a contact section which has a cavity permitting said puncture needle to pass therethrough and which comes into contact with a skin;

a measurement unit for measuring a component of blood sampled; and

a blood introduction section spaced from said puncture needle in a direction substantially orthogonal to the axis of said puncture needle and communicating with said measurement unit, and

after the skin is punctured by said puncture needle, said blood introduction section is displaced in a direction substantially orthogonal to the axis of said puncture needle and the axial direction of said puncture needle toward the skin.

2. The blood component measurement device as set forth in claim 1,

wherein said blood component measurement device further includes a guide section holding said contact section in a manner permitting displacement of the contact section in a direction that is neither parallel nor perpendicular to the axis of said puncture needle, and

said blood introduction section is displaced under a guiding action of said guide section.

3. The blood component measurement device as set forth in claim 1,

wherein said contact section forms a part of said tip for blood measurement.

4. The blood component measurement device as set forth in claim 1,

wherein said blood introduction section forms a part of said tip for blood measurement.

5. The blood component measurement device as set forth in claim 1,

wherein said measurement unit forms a part of said tip for blood measurement.

6. The blood component measurement device as set forth in claim 1,

wherein said blood component measurement device includes a stopper which contacts the contact section for restricting displacement of said contact section, the stopper moving out of contact with the contact section after puncture of the skin by the puncture needle to permit the displacement of the contact section.

7. The blood component measurement device as set forth in claim 2,

wherein said contact section is provided with a first slant surface (82) opposed to said guide section and inclined at a predetermined angle, said guide section is provided with a second slant surface making contact with said first slant surface, the first slant surface and the second slant surface are oriented at substantially the same angle, and said contact section is displaced relative to said guide section as a result of said first slant surface sliding along said second slant surface.

8. The blood component measurement device as set forth in claim 1,

wherein said blood component measurement device includes a housing, a button unit displaceably disposed inside said housing and operable to cancel a condition where the advancing and retreating of said puncture needle are restricted, and said button unit is exposed from said housing when said contact section is pressed against the skin.

9. (canceled)

10. (canceled)

11. A tip for blood measurement, comprising:

a mounted section to be mounted to a blood component measurement device;

a puncture needle possessing an axis and movable for being advanced and retreated in an axial direction of the needle;

a contact section which has a cavity permitting said puncture needle to pass therethrough and which comes into contact with a skin; and

a measurement unit for measuring a component of blood sampled,

wherein said contact section is so held as to be displaceable in the axial direction of said puncture needle relative to said mounted section

12. A tip for blood component measurement comprising;

a puncture needle possessing an axis, the needle being movable in an axial direction of the needle to perform advancing movement and retracting movement;

a contact section adapted to contact skin and having a cavity through which the needle is moved during the advancing movement of the needle;

a measurement unit for measuring a component of blood sampled;

a blood introduction section spaced from the puncture needle in a direction substantially orthogonal to the axis of the puncture needle and in communication with the measurement unit;

a guide block having a guide block surface in sliding contact with a contact section surface of the contact section so that relative movement between the contact section and the guide block is permitted;

the puncture needle and the blood introduction section being provided on the guide block;

at least one of the guide block surface and the contact section surface being a slanting surface that is obliquely oriented relative to the axis of the needle so that the relative movement is in a direction oblique to the axis of the needle.

13. The tip for blood component measurement as set forth in claim 12, wherein the contact section surface is a first slant surface and the guide block surface is a second slant surface opposed to the first slant surface, both of said first and second slant surfaces being oriented at a common angle relative to the axis of the needle.

14. The tip for blood component measurement as set forth in claim 13, wherein the contact section includes a pair of first slant surfaces and the guide block includes a pair of second slant surfaces, each of the first slant surfaces being in sliding contact with one of the second slant surfaces.

15. The tip for blood component measurement as set forth in claim 12, wherein the needle is held in a hub that is slidably positioned inside the guide block.

16. A tip for blood component measurement comprising;

a contact section adapted to be contacted by skin of a patient whose blood component is to be measured, the contact section comprising a through hole;

a guide section positioned adjacent the contact section and comprising a needle movably mounted in a holding hole in the guide block for movement in an advancing direction relative to the contact section to move a tip end of the needle through the through hole of the contact section to puncture the skin and thereby result in a blood sample, the holding hole possessing an axis;

the guide block comprising a blood introduction part comprised of an introduction port and a passage, the introduction port being orthogonally spaced from the axis of the holding hole;

the guide block being provided with a recess adapted to receive a test paper impregnated with a reagent;

the recess in the guide block communicating with the introduction port by way of the passage so that the blood sample introduced into the introduction port is conveyed to the recess by way of the passage, the introduction port being spaced from the axis of the needle;

a measurement unit positioned in opposition to the recess to measure a component in the blood sample;

the contact section and the guide section being relatively movable between a first relative position in which the tip end of the needle is located in a first region of the through hole while the introduction port is spaced from said first region, and a second relative position in which the introduction port is located in said first region of the through hole while the tip end of the needle is spaced from said first region.

17. The tip for blood component measurement as set forth in claim 16, wherein the contact section includes a first slant surface angled at an oblique angle relative to the axis of the holding hole, and the guide block includes a second slant surface, the first slant surface being in sliding engagement with the second slant surface during movement between the first and second relative positions.

18. tip for blood component measurement as set forth in claim 16, wherein the needle is held in a hub that is slidably positioned in the holding hole of the guide block.

19. The tip for blood component measurement as set forth in claim 16, wherein the introduction port in the second relative position is positioned more forwardly relative to the contact section than in the first relative position, and wherein the tip end of the needle in the first relative position is positioned more forwardly relative to the contact section than in the second relative position.

20. The tip for blood component measurement as set forth in claim 16, wherein the holding hole opens to one side surface of the guide block, and the introduction portion extends outwardly from the one side surface of the guide block.

21. A method for obtaining a blood sample comprising:

pressing a body part against a contact section which possesses a through hole;

moving a needle in an advancing direction through the through hole in the contact section to puncture skin of the body part at a puncture site with a tip end of the needle to result in a blood sample, the tip end of the needle possessing an axis and being located in a first region of the through hole during puncture of the skin, the needle being mounted in a guide block which is movable relative to the control section, the guide block including a blood introduction port connected to a passage, the blood introduction port being orthogonally spaced from the axis of the tip end of the needle and outside the first region;

relatively moving the guide block and the contact section after the puncture of the skin to move the tip end of the needle away from said first region of the through hole of the contact section and to move the introduction port into the first region of the through hole of the contact section so that the introduction port is positioned adjacent the puncture site;

the blood sample at the puncture site being introduced into the introduction port and supplied to a test paper containing a reagent; and

measuring a component in the blood sample supplied to the test paper.

22. The method according to claim 21, wherein the first region of the through hole of the control section is a center of the through hole of the control section.

23. The method according to claim 21, wherein the relatively moving of the guide block and the control section comprises the guide block and the control section sliding relative to one another in a direction oblique to the axis of the tip end of the needle.