DEVICES AND METHODS FOR EMBOLUS REMOVAL DURING ACUTE ISCHEMIC STROKE

• US 20090105722A1
• Filed: 07/30/2008
• Published: 04/23/2009
• Est. Priority Date: 10/17/2007
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Mindframe LLC
• Inventors: Fulkerson, John, Ferrera, David A.
• Granted Patent: US 9,220,522 B2
• Time in Patent Office: Days
• US Class Current: 606/127
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 2017/22039 eccentric
• CPC Class Codes: A61B 2017/22094 for crossing total occlusions, i.e. piercing
• CPC Class Codes: A61B 2017/2212 having a closed distal end, e.g. a loop
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61F 2002/018 made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61F 2230/0006 circular
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61M 25/09 Guide wires
• CPC Class Codes: A61M 25/09025 with sliding mandrils

Abstract

Devices, methods, and systems facilitate and enable treatment of ischemic stroke. More specifically, a tethered basket-like system operates in conjunction with a microcatheter system, to provide arterial support and capture emboli.

Claims

1. An improved device for the removal of emboli comprising:

a mesh capturer/basket having at least an undeployed state and a deployed state, the mesh capturer being inserted into the neurovasculature in an undeployed state and removed from the microvasculature in its retracted state;

wherein the mesh capturer is deployed into its deployed state distal to an embolus and advanced proximally until the embolus is substantially contained within the mesh capturer;

wherein the mesh capturer/basket is deployed above the subclavian artery and common carotid artery.

2. The improved device of claim 1, wherein said mesh capturer/basket is eccentric.

3. The improved device of claim 2, whereby the eccentricity of said mesh capturer/basket at the proximal end improves capture of emboli and clots because of its geometric configuration.

4. The improved device of claim 3, further comprised of uniformly sized struts.

5. The improved device of claim 3, comprising struts having increased thickness adjacent to the proximate end.

6. The improved device of claim 4, having radiopacity at a distal end of the device.

7. The improved device of claim 6, said radiopacity further comprised of at least a peg, selected from the group consisting of platinum and gold, the peg being pressed into pre-laser cut apertures.

8. The improved device of claim 7, further comprising:

a proximal stainless steel pusher and distal nitinol device.

9. The improved device of claim 8, wherein a polymeric liner is incorporated within the pusher to improve guidewire trackability.

10. The improved device of claim 9, where the polymeric liner is extended beyond the distal tip of the pusher to a length greater than the length of the nitinol device.

11. The improved device of claim 10 whereby guidewire entanglement in the nitinol device is prevented, by the extended polymeric liner.

12. The improved device of claim 11, further comprising uniform cells.

13. A method for removing an embolus comprising:

inserting a microcatheter distal to an embolus;

inserting a embolus capture device distal to the microcatheter distal to the embolus;

deploying the embolus capture device;

retracting the deployed embolus capture device until the embolus is substantially contained within the embolus capture device; and

removing the embolus capture device.

14. The method of claim 13, wherein the embolus capture device is deployed over a guidewire.

15. The method of claim 14, wherein the embolus capture device is deployed as a component of a rapid exchange system.

16. The method of claim 14, wherein a foreign body is the target of removal.

17. the method of claim 16, wherein the foreign body is a microcoil.

18. The method of claim 16, wherein said foreign body is a medical device.

19. The method of claim 16 wherein the said foreign body is a kidney stone.

20. The method of claim 16, wherein the said foreign body is a gallstone.