Insertion and extraction tools for lacrimal implants

• US 20090105749A1
• Filed: 09/05/2008
• Published: 04/23/2009
• Est. Priority Date: 09/07/2007
• Status: Abandoned Application

• Current Assignee: Mati Therapeutics, Inc
• Original Assignee: QLT Plug Delivery, Inc.
• Inventors: de Juan, Eugene, Kjellbotn, Charles Richard, Reich, Cary J., Boyd, Stephen, Rapacki, Alan R., Rubinchik, Valery, Shimizu, Robert W.
• Application Number:
  US12/231,984
• Publication Number:
  US 20090105749A1
• Time in Patent Office: Days
• US Class Current: 606/206
• CPC Class Codes: A61B 17/3468 for implanting or removing devices, e.g. prostheses, implants, seeds, wires devices for implanting seeds A61M37/0069
• CPC Class Codes: A61B 2090/036 abutting on tissue or skin
• CPC Class Codes: A61F 9/00772 Apparatus for restoration of tear ducts

Abstract

Insertion and extraction tool, systems, and methods for use with lacrimal implants. An insertion tool is disclosed that includes a proximal end, a distal end, and a tool body therebetween. The distal end includes a mechanical coupling to receive a cartridge preloaded with a lacrimal implant, and a plunger configured to dispense the lacrimal implant from a preloaded cartridge.

Claims

1. An implant insertion tool for use with a lacrimal implant, the insertion tool comprising:

a proximal end, a distal end, and a tool body therebetween, wherein the distal end includes;

a mechanical coupling to receive a cartridge preloaded with a lacrimal implant; and

a plunger configured to dispense the lacrimal implant from a preloaded cartridge.

2. The insertion tool of claim 1, wherein the cartridge engages an outer surface of the lacrimal implant and contains an inner lumen, wherein the plunger has a diameter greater than or equal to a diameter of a plunger receiving surface of the lacrimal implant and the plunger is configured to slide within the inner lumen and engage and dispense the lacrimal implant from the cartridge.

3. The insertion tool of claim 1, wherein the proximal end includes an insertion facilitating portion.

4. The insertion tool of claim 3, wherein the insertion facilitating portion includes a curvature substantially similar to a curvature of at least a portion of the lacrimal implant.

5. The insertion tool of claim 1, wherein the insertion tool includes a living hinge coupled to the plunger, and wherein manipulating the living hinge causes the plunger to dispense the lacrimal implant.

6. A system for treatment of the eye, comprising:

a lacrimal implant;

a cartridge configured to hold the lacrimal implant;

a lacrimal implant insertion tool for use with the lacrimal implant, the insertion tool comprising;

a proximal end, a distal end, and a tool body therebetween, wherein the distal end includes;

a mechanical coupling to receive the cartridge; and

a plunger configured to dispense the lacrimal implant from the cartridge.

7. The system of claim 6, wherein the plunger has a diameter greater than or equal to a diameter of a plunger receiving surface of the lacrimal implant.

8. The system of claim 7, wherein the lacrimal implant includes a drug eluting portion and a plug portion surrounding at least a portion of the drug eluting portion, and wherein the plunger diameter is greater than or equal to a diameter of the plug portion, and wherein the plunger engages the plug portion to dispense the lacrimal implant.

9. The system of claim 6, wherein the cartridge is rotatable relative to the distal end of the insertion tool.

10. The insertion tool of claim 6, wherein the proximal end of the insertion tool includes an insertion facilitating portion, wherein the insertion facilitating portion includes a curvature substantially similar to a curvature of at least one of the drug eluting portion and the plug portion of the lacrimal implant.

11. An implant insertion tool for use with a lacrimal implant, the insertion tool comprising:

a proximal end, a distal end, and a tool body therebetween;

a forceps located at the distal end, wherein the forceps are sized to engage the lacrimal implant on an outer surface of the implant, and wherein the insertion tool is configured to lock a position of the forceps when the lacrimal implant is so engaged.

12. The insertion tool of claim 11, including a collar to slidably engage the forceps to cause the forceps to open and close.

13. The insertion tool of claim 12, including a lever located on the tool body, wherein manipulating the lever causes the collar to slidably engage the forceps.

14. The insertion tool of claim 11, wherein an end of each arm of the forceps includes a groove substantially perpendicular to the forceps arm, wherein the grooves are sized to receive at least a portion of the lacrimal implant when the forceps are closed.

15. The insertion tool of claim 14, wherein at least one of the forceps arms includes a stop to engage an end of the lacrimal implant and inhibit movement of the lacrimal implant relative to the forceps.

16. The insertion tool of claim 11, wherein the proximal end includes an insertion facilitating portion.

17. The insertion tool of claim 11, wherein the proximal end of the insertion tool includes a second forceps configured to extract the lacrimal implant from the punctum.

18. The insertion tool of claim 11, wherein the forceps are detachable from the tool body.

19. A method of inserting an implant using an insertion tool, the method comprising:

preloading a lacrimal implant into a cartridge; and

dispensing the lacrimal implant from the cartridge to insert the lacrimal implant into a punctum.

20. The method of claim 19, wherein preloading a lacrimal implant into a cartridge includes engaging an outer surface of the lacrimal implant to releasably support the lacrimal implant.

21. The method of claim 19, wherein dispensing the lacrimal implant includes dispensing the lacrimal implant from the cartridge using a plunger.

22. The method of claim 21, including manipulating a living hinge on the insertion tool to engage the lacrimal implant with the plunger.

23. A method of inserting an implant using an insertion tool, the method comprising:

engaging an outer surface of the lacrimal implant with a forceps;

locking a forceps position when the outer surface of the lacrimal implant is engaged; and

advancing the lacrimal implant into a punctum.

24. The method of claim 23, including slidably engaging arms of the forceps with a collar to open and close the forceps.

25. The method of claim 24, wherein slidably engaging arms of the forceps with a collar includes manipulating a lever to cause the collar to slidably engage the arms of the forceps.

26. The method of claim 24, including receiving the lacrimal implant into a groove on a forcep arm when the forceps are closed, wherein the groove is substantially perpendicular to the forcep arm and is sized to receive the lacrimal implant.

27. The method of claim 23, wherein advancing the lacrimal implant into the punctum includes engaging an end of the lacrimal implant with a stop on a forcep arm to inhibit movement of the lacrimal implant relative to the forcep arm.

28. The method of claim 23, including changing the forceps of the insertion tool to fit a geometry of the lacrimal implant.

29. An implant insertion tool for insertion of a lacrimal implant into a punctum of a patient, the insertion tool comprising:

a tool body having a distal portion configured to hold the implant on an outer implant surface, the distal portion having an inner lumen with an internal depth stop; and

a plunger slidable within the inner lumen to engage and dispense the implant, the plunger having a stop configured to engage with the internal depth stop, wherein the engagement of the stop and the internal depth stop limits an insertion depth of the implant into the punctum.

30. An implant insertion tool for use with a lacrimal implant, the insertion tool comprising:

a tool body having a proximal handle, a distal end, and an axis therebetween, the tool body including;

an implant receptacle releasably supporting, on at least one outer implant surface, the lacrimal implant relative to the handle, such that the lacrimal implant is advanceable distally into a canalicular lumen by manipulation of the handle; and

a tissue-engagement stop surface, the stop surface being distally oriented and configured to engage an anteriorly oriented tissue surface to inhibit distal insertion of the lacrimal implant beyond a target insertion depth.

31. A lacrimal implant insertion system for treatment of one or more tissues near a punctum of a patient, the punctum disposed between a canalicular lumen and an anteriorly oriented tissue surface of the patient, the lacrimal implant system comprising:

a self-dilating lacrimal implant; and

an insertion tool having a proximal handle, a distal implant receptacle, and an axis therebetween, the implant receptacle releasably supporting the lacrimal implant such that the lacrimal implant is advanceable distally into the canalicular lumen by manipulation of the handle, the insertion tool including a tissue-engagement stop surface, the stop surface being distally oriented and configured to engage the anteriorly oriented tissue surface so as to inhibit distal insertion of the lacrimal implant beyond a target insertion depth.

32. A method of inserting an implant into a punctum of a patient using an insertion tool, the method comprising:

advancing the implant distally into the punctum;

engaging a tissue stop of the insertion tool against a tissue surface of the punctum so as to inhibit distal movement of the insertion tool; and

detaching the implant from the insertion tool while the tissue stop engages the tissue surface and while the implant is aligned axially relative to the tissue stop so that the implant is implanted at a target depth within the canalicular lumen.

33. A method of inserting an implant into a punctum of a patient using an insertion tool, the method comprising:

placing a tissue stop of the insertion tool proximate the punctum;

moving a plunger within the insertion tool forward, thereby inserting the implant into the punctum; and

stopping the plunger movement when a stop on the plunger engages an internal depth stop of the insertion tool, wherein the engagement of the stop and internal depth stop limits the depth of insertion of the implant into the punctum.

34. An extraction tool for extraction of an implant from a punctum of a patient, the extraction tool comprising:

an extraction tool body having a distal portion, wherein the distal portion includes an extraction feature to engage a complimentary extraction feature of the implant.

35. An extraction tool for extraction of an implant from a punctum of a patient, the extraction tool comprising:

an extraction tool body having a distal portion; and

a suction device configured to provide a suction force to the extraction tool body, wherein the distal portion of the extraction tool includes an inner lumen extending to a tip of the distal portion, and wherein the tip is configured to engage the punctum and apply the suction force to extract the implant.