Devices and systems that deliver nitric oxide

• US 20090108777A1
• Filed: 04/16/2008
• Published: 04/30/2009
• Est. Priority Date: 10/30/2007
• Status: Active Grant

• Current Assignee: Gearbox LLC (Intellectual Ventures LLC)
• Original Assignee: Searete LLC (Intellectual Ventures LLC)
• Inventors: Stordal, Leif T., Ishikawa, Muriel Y., Wood, Lowell L. JR., Hyde, Roderick A.
• Granted Patent: US 8,877,508 B2
• Time in Patent Office: Days
• US Class Current: 315/307
• CPC Class Codes: A61K 33/00 Medicinal preparations containing inorganic active ingredients
• CPC Class Codes: A61K 41/0042 Photocleavage of drugs in vivo, e.g. cleavage of photolabile linkers in vivo by UV radiation for releasing the pharmacologically-active agent from the administered agent; photothrombosis or photoocclusion
• CPC Class Codes: A61K 9/7084 Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
• CPC Class Codes: Y10T 436/12 Condition responsive control

Abstract

The present disclosure relates to dressings, such as patches and bandages, and other devices and systems that deliver nitric oxide.

Claims

1-123. -123. (canceled)

124. A system comprising:

circuitry for operating one or more light sources that are operably associated with one or more photolyzable nitric oxide donors and one or more backing sheets.

125. The system of claim 124, wherein the circuitry for operating one or more light sources that are operably associated with one or more photolyzable nitric oxide donors and one or more backing sheets comprises:

circuitry for operating one or more light emitters.

126. The system of claim 124, wherein the circuitry for operating one or more light sources that are operably associated with one or more photolyzable nitric oxide donors and one or more backing sheets comprises:

circuitry for operating one or more power supplies.

127. The system of claim 124, wherein the circuitry for operating one or more light sources that are operably associated with one or more photolyzable nitric oxide donors and one or more backing sheets comprises:

circuitry for operating one or more electromagnetic receivers.

128. The system of claim 124, wherein the circuitry for operating one or more light sources that are operably associated with one or more photolyzable nitric oxide donors and one or more backing sheets comprises:

circuitry for operating one or more control units.

131. The system of claim 124, wherein the circuitry for operating one or more light sources that are operably associated with one or more photolyzable nitric oxide donors and one or more backing sheets comprises:

circuitry for operating the one or more light sources that are associated with one or more photolyzable nitric oxide donors through one or more optical waveguides.

132. The system of claim 124, wherein the circuitry for operating one or more light sources that are operably associated with one or more photolyzable nitric oxide donors and one or more backing sheets comprises:

circuitry for operating the one or more light sources that include one or more quantum dots.

134. The system of claim 124, wherein the circuitry for operating one or more light sources that are operably associated with one or more photolyzable nitric oxide donors and one or more backing sheets comprises:

circuitry for operating the one or more light sources that are associated with one or more rare-earth materials.

136. The system of claim 124, wherein the circuitry for operating one or more light sources that are operably associated with one or more photolyzable nitric oxide donors and one or more backing sheets comprises:

circuitry for operating the one or more light sources that include one or more light emitting diodes.

138. The system of claim 124, wherein the circuitry for operating one or more light sources that are operably associated with one or more photolyzable nitric oxide donors and one or more backing sheets comprises:

circuitry for operating the one or more light sources that emit visible light.

139. The system of claim 124, wherein the circuitry for operating one or more light sources that are operably associated with one or more photolyzable nitric oxide donors and one or more backing sheets comprises:

circuitry for operating the one or more light sources that emit infrared light.

140. The system of claim 124, wherein the circuitry for operating one or more light sources that are operably associated with one or more photolyzable nitric oxide donors and one or more backing sheets comprises:

circuitry for operating the one or more light sources that are configured to emit light that specifically facilitates release of nitric oxide from the one or more nitric oxide donors.

141. The system of claim 124, wherein the circuitry for operating one or more light sources that are operably associated with one or more photolyzable nitric oxide donors and one or more backing sheets comprises:

circuitry for operating the one or more light sources that are configured to emit light that specifically selected to avoid damaging one or more tissues.

142. The system of claim 124, further comprising:

circuitry for operating one or more control units.

143. The system of claim 142, wherein the circuitry for operating one or more control units comprises:

circuitry for operating the one or more control units that are operably associated with the one or more light sources.

145. The system of claim 142, wherein the circuitry for operating one or more control units comprises:

circuitry for operating one or more receivers that are configured to receive one or more signals.

147. The system of claim 142, wherein the circuitry for operating one or more control units comprises:

circuitry for operating one or more transmitters.

148. The system of claim 142, wherein the circuitry for operating one or more control units comprises:

circuitry for operating the one or more control units that regulate the one or more light sources.

155. The system of claim 142, wherein the circuitry for operating one or more control units comprises:

circuitry for operating the one or more control units that regulate in response to one or more programs.

156. The system of claim 142, wherein the circuitry for operating one or more control units comprises:

circuitry for operating the one or more control units that regulate in response to one or more commands.

160. The system of claim 142, wherein the circuitry for operating one or more control units comprises:

circuitry for operating the one or more control units that regulate one or more associations of one or more light sources with one or more photolyzable nitric oxide donors.

161. The system of claim 142, further comprising:

circuitry for operating one or more sensors.

163. The system of claim 161, wherein the circuitry for operating one or more sensors comprises:

circuitry for operating the one or more sensors that are configured to detect temperature.

164. The system of claim 161, wherein the circuitry for operating one or more sensors comprises:

circuitry for operating the one or more sensors that are configured to detect hydrostatic pressure.

165. The system of claim 161, wherein the circuitry for operating one or more sensors comprises:

circuitry for operating the one or more sensors that are configured to detect one or more microbes.

166. The system of claim 161, wherein the circuitry for operating one or more sensors comprises:

circuitry for operating the one or more sensors that are configured to detect nitric oxide.

168. The system of claim 161, wherein the circuitry for operating one or more sensors comprises:

circuitry for operating the one or more sensors that are configured to detect one or more nitric oxide donors.

169. The system of claim 161, wherein the circuitry for operating one or more sensors comprises:

circuitry for operating the one or more sensors that are operably coupled to the one or more control units.

171. The system of claim 161, wherein the circuitry for operating one or more sensors comprises:

circuitry for operating the one or more sensors that are configured to transmit one or more signals.

172. The system of claim 161, wherein the circuitry for operating one or more sensors comprises:

circuitry for operating the one or more sensors that include one or more electrochemical sensors.

173. The system of claim 161, wherein the circuitry for operating one or more sensors comprises:

circuitry for operating the one or more sensors that include one or more semiconductor sensors.

174. The system of claim 161, wherein the circuitry for operating one or more sensors comprises:

circuitry for operating the one or more sensors that include one or more chemical sensors.

129-130. -130. (canceled)

133. (canceled)

135. (canceled)

137. (canceled)

144. (canceled)

146. (canceled)

149-154. -154. (canceled)

157-159. -159. (canceled)

162. (canceled)

167. (canceled)

170. (canceled)

175-177. -177. (canceled)

178. A system comprising:

means for operating one or more light sources that are operably associated with one or more backing sheets.

179. The system of claim 178, further comprising:

means for operating one or more control units.

180. The system of claim 179, further comprising:

means for operating one or more sensors.

181. A system comprising:

a signal-bearing medium bearing;

one or more instructions for operating one or more light sources that are operably associated with one or more backing sheets.

182. The system of claim 181, wherein the signal-bearing medium includes a computer-readable medium.

183. The system of claim 181, wherein the signal-bearing medium includes a recordable medium.

184. The system of claim 181, wherein the signal-bearing medium includes a communications medium.

185. The system of claim 181, further comprising:

one or more instructions for operating one or more control units.

186. The system of claim 185, further comprising:

one or more instructions for operating one or more sensors.