METHOD FOR ADAPTING FRACTIONATION OF A RADIATION THERAPY DOSE
First Claim
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1. A method of adapting a treatment plan, the method comprising:
- preparing a treatment plan for a patient, the treatment plan including multiple treatment fractions each having a planned radiation dose to be delivered to the patient;
identifying a position of a first structure relative to a second structure prior to delivering each one of the fractions,prior to delivering the present treatment fraction, adjusting the planned radiation dose to be delivered to the patient for the present treatment fraction based on the position of the first structure relative to the second structure without replanning the treatment plan; and
delivering the adjusted planned radiation dose to the patient.
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Abstract
A system and method of adapting a radiation therapy treatment plan for a patient by varying the fraction size delivered to the patient on any individual day, based at least partially on the use of daily patient registration (i.e., taking images of the patient before each fraction is delivered to see the position and size of the tumor on that day). The fraction size can be dynamically altered based upon the biology of the tumor.
160 Citations
38 Claims
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1. A method of adapting a treatment plan, the method comprising:
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preparing a treatment plan for a patient, the treatment plan including multiple treatment fractions each having a planned radiation dose to be delivered to the patient; identifying a position of a first structure relative to a second structure prior to delivering each one of the fractions, prior to delivering the present treatment fraction, adjusting the planned radiation dose to be delivered to the patient for the present treatment fraction based on the position of the first structure relative to the second structure without replanning the treatment plan; and delivering the adjusted planned radiation dose to the patient. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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17. A method of treating a patient with radiation therapy using a plurality of fractions to deliver a total planned radiation dose to a tumor volume that has a sensitive structure in physical proximity to a tumor volume, the method comprising:
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preparing a treatment plan for a patient, the treatment plan including multiple treatment fractions each having a planned delivered dose; acquiring an image of the patient; using the acquired information to adjust the dose to be delivered for a given treatment fraction; and delivering radiation to the patient according to the treatment plan such that the adjusted dose is delivered to the patient. - View Dependent Claims (18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36)
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37. A radiation therapy treatment system for adapting a treatment plan, the radiation therapy treatment system comprising:
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a computer processor; and a software program stored in a computer readable medium accessible by the computer processor, the software being operable to generate a treatment plan for a patient, the treatment plan including multiple treatment fractions each having an associated planned delivered dose to be delivered to the patient, identify a position of a first structure relative to a second structure prior to delivery of each one of the fractions, prior to delivery of the present treatment fraction, adjust the planned radiation dose to be delivered to the patient for the present treatment fraction based on the position of the first structure relative to the second structure without the treatment plan being replanned, and deliver the adjusted planned radiation dose to the patient.
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38. A computer program embodied by a computer readable medium capable of being executed by a computer, the computer program for use in a radiation therapy treatment system, the computer program comprising:
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a treatment plan module operable to generate a treatment plan for a patient, the treatment plan including multiple treatment fractions each having an associated planned delivered dose to be delivered to the patient; a patient position module operable to identify a position of a first structure relative to a second structure prior to delivery of each one of the fractions; a fraction modification module operable to, prior to delivery of the present treatment fraction, adjust the planned radiation dose to be delivered to the patient for the present treatment fraction based on the position of the first structure relative to the second structure without the treatment plan being replanned; and a treatment delivery module operable to deliver the adjusted planned radiation dose to the patient.
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Specification