Substrates for nitric oxide releasing devices

• US 20090110604A1
• Filed: 01/11/2008
• Published: 04/30/2009
• Est. Priority Date: 10/30/2007
• Status: Active Grant

• Current Assignee: Gearbox LLC (Intellectual Ventures LLC)
• Original Assignee: Searete LLC (Intellectual Ventures LLC)
• Inventors: Stordal, Leif T., Ishikawa, Muriel Y., Wood, Lowell L. JR., Hyde, Roderick A.
• Granted Patent: US 7,846,400 B2
• Time in Patent Office: Days
• US Class Current: 422/83
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 33/00 Medicinal preparations containing inorganic active ingredients
• CPC Class Codes: A61L 2300/114 Nitric oxide, i.e. NO
• CPC Class Codes: A61L 31/16 Biologically active materials, e.g. therapeutic substances A61L31/047 takes precedence
• CPC Class Codes: C01B 21/24 Nitric oxide (NO) C01B21/203 takes precedence

Abstract

The present disclosure relates to substrates associated with nitric oxide.

Claims

1. An apparatus comprising:

one or more substrates that are configured for operable association with one or more light sources that are configured to emit light that facilitates release of nitric oxide from one or more photolyzable nitric oxide donors.

2. The apparatus of claim 1, wherein the one or more substrates that are configured for operable association with one or more light sources that are configured to emit light that facilitates release of nitric oxide from one or more photolyzable nitric oxide donors comprise:

one or more fluid impermeable substrates.

3. The apparatus of claim 1, wherein the one or more substrates that are configured for operable association with one or more light sources that are configured to emit light that facilitates release of nitric oxide from one or more photolyzable nitric oxide donors comprise:

one or more gas impermeable substrates.

7. The apparatus of claim 1, wherein the one or more substrates that are configured for operable association with one or more light sources that are configured to emit light that facilitates release of nitric oxide from one or more photolyzable nitric oxide donors comprise:

one or more substrates that are permeable to nitric oxide.

8. The apparatus of claim 1, wherein the one or more substrates that are configured for operable association with one or more light sources that are configured to emit light that facilitates release of nitric oxide from one or more photolyzable nitric oxide donors comprise:

one or more adhesives.

11. The apparatus of claim 1, wherein the one or more substrates that are configured for operable association with one or more light sources that are configured to emit light that facilitates release of nitric oxide from one or more photolyzable nitric oxide donors comprise:

one or more metallic substrates.

15. The apparatus of claim 1, wherein the one or more substrates that are configured for operable association with one or more light sources that are configured to emit light that facilitates release of nitric oxide from one or more photolyzable nitric oxide donors comprise:

one or more vapor permeable substrates.

16. The apparatus of claim 1, wherein the one or more substrates that are configured for operable association with one or more light sources that are configured to emit light that facilitates release of nitric oxide from one or more photolyzable nitric oxide donors comprise:

one or more light permeable substrates.

17. The apparatus of claim 1, wherein the one or more substrates that are configured for operable association with one or more light sources that are configured to emit light that facilitates release of nitric oxide from one or more photolyzable nitric oxide donors comprise:

one or more sensors.

18. The apparatus of claim 1, wherein the one or more substrates that are configured for operable association with one or more light sources that are configured to emit light that facilitates release of nitric oxide from one or more photolyzable nitric oxide donors comprise:

one or more sensors that are configured to detect nitric oxide.

19. The apparatus of claim 1, wherein the one or more substrates that are configured for operable association with one or more light sources that are configured to emit light that facilitates release of nitric oxide from one or more photolyzable nitric oxide donors comprise:

one or more sensors that are configured to detect one or more nitric oxide donors.

21. The apparatus of claim 1, wherein the one or more substrates that are configured for operable association with one or more light sources that are configured to emit light that facilitates release of nitric oxide from one or more photolyzable nitric oxide donors comprise:

one or more substrates that include one or more connections configured for operable association with the one or more light sources.

22. The apparatus of claim 1, wherein the one or more substrates that are configured for operable association with one or more light sources that are configured to emit light that facilitates release of nitric oxide from one or more photolyzable nitric oxide donors comprise:

one or more substrates that are configured to associate with one or more batteries.

24. The apparatus of claim 1, wherein the one or more substrates that are configured for operable association with one or more light sources that are configured to emit light that facilitates release of nitric oxide from one or more photolyzable nitric oxide donors comprise:

one or more substrates that are configured to associate with one or more nitric oxide donors.

25. The apparatus of claim 1, wherein the one or more substrates that are configured for operable association with one or more light sources that are configured to emit light that facilitates release of nitric oxide from one or more photolyzable nitric oxide donors comprise:

one or more substrates that include one or more operably coupled photolyzable nitric oxide donors.

27. The apparatus of claim 1, wherein the one or more substrates that are configured for operable association with one or more light sources that are configured to emit light that facilitates release of nitric oxide from one or more photolyzable nitric oxide donors comprise:

one or more status indicators.

28. The apparatus of claim 1, wherein the one or more substrates that are configured for operable association with one or more light sources that are configured to emit light that facilitates release of nitric oxide from one or more photolyzable nitric oxide donors comprise:

one or more control units that are configured to control one or more remote light sources.

29. The apparatus of claim 1, further comprising:

one or more photolyzable nitric oxide donors.

30. The apparatus of claim 29, wherein the one or more photolyzable nitric oxide donors comprise:

one or more photolyzable nitric oxide donors that include one or more diazeniumdiolates.

31. The apparatus of claim 29, wherein the one or more photolyzable nitric oxide donors comprise:

one or more photolyzable nitric oxide donors that are associated with one or more quantum dots.

32. The apparatus of claim 29, wherein the one or more photolyzable nitric oxide donors comprise:

one or more photolyzable nitric oxide donors that are associated with one or more fluorescent materials.

33. The apparatus of claim 29, wherein the one or more photolyzable nitric oxide donors comprise:

one or more photolyzable nitric oxide donors that are associated with one or more rare-earth materials.

35. The apparatus of claim 29, wherein the one or more photolyzable nitric oxide donors comprise:

one or more photolyzable nitric oxide donors that are coupled to one or more polymeric materials.

36. The apparatus of claim 1, further comprising:

one or more light sources that are configured to emit light that facilitates release of nitric oxide from the one or more photolyzable nitric oxide donors.

38. The apparatus of claim 36, wherein the one or more light sources that are configured to emit light that facilitates release of nitric oxide from the one or more photolyzable nitric oxide donors comprise:

one or more light emitters that are configured to selectively emit one or more wavelengths of light that correspond to the absorption maximum of the one or more photolyzable nitric oxide donors.

39. The apparatus of claim 36, wherein the one or more light sources that are configured to emit light that facilitates release of nitric oxide from the one or more photolyzable nitric oxide donors comprise:

one or more light emitters that are configured to selectively emit one or more wavelengths of light that facilitate photodecomposition of the one or more photolyzable nitric oxide donors.

40. The apparatus of claim 36, wherein the one or more light sources that are configured to emit light that facilitates release of nitric oxide from the one or more photolyzable nitric oxide donors comprise:

one or more light emitters that are configured to emit light that is selected to avoid damaging one or more tissues.

41. The apparatus of claim 36, wherein the one or more light sources that are configured to emit light that facilitates release of nitric oxide from the one or more photolyzable nitric oxide donors comprise:

one or more optical waveguides.

42. The apparatus of claim 36, wherein the one or more light sources that are configured to emit light that facilitates release of nitric oxide from the one or more photolyzable nitric oxide donors comprise:

one or more control units.

43. The apparatus of claim 36, wherein the one or more light sources that are configured to emit light that facilitates release of nitric oxide from the one or more photolyzable nitric oxide donors comprise:

one or more optical fibers.

45. The apparatus of claim 36, wherein the one or more light sources that are configured to emit light that facilitates release of nitric oxide from the one or more photolyzable nitric oxide donors comprise:

one or more power supplies.

47. The apparatus of claim 36, wherein the one or more light sources that are configured to emit light that facilitates release of nitric oxide from the one or more photolyzable nitric oxide donors comprise:

one or more power supplies that include one or more solar cells.

49. The apparatus of claim 36, wherein the one or more light sources that are configured to emit light that facilitates release of nitric oxide from the one or more photolyzable nitric oxide donors comprise:

one or more electromagnetic receivers.

50. The apparatus of claim 36, wherein the one or more light sources that are configured to emit light that facilitates release of nitric oxide from the one or more photolyzable nitric oxide donors comprise:

one or more light sources that are coated with at least one of the one or more photolyzable nitric oxide donors.

51. The apparatus of claim 36, wherein the one or more light sources that are configured to emit light that facilitates release of nitric oxide from the one or more photolyzable nitric oxide donors comprise:

one or more light sources that are associated with one or more quantum dots.

52. The apparatus of claim 36, wherein the one or more light sources that are configured to emit light that facilitates release of nitric oxide from the one or more photolyzable nitric oxide donors comprise:

one or more light sources that are associated with one or more optically transmitting materials.

53. The apparatus of claim 36, wherein the one or more light sources that are configured to emit light that facilitates release of nitric oxide from the one or more photolyzable nitric oxide donors comprise:

one or more light sources that are associated with one or more fluorescent materials.

54. The apparatus of claim 36, wherein the one or more light sources that are configured to emit light that facilitates release of nitric oxide from the one or more photolyzable nitric oxide donors comprise:

one or more light sources that are associated with one or more rare-earth materials.

59. The apparatus of claim 36, wherein the one or more light sources that are configured to emit light that facilitates release of nitric oxide from the one or more photolyzable nitric oxide donors comprise:

one or more light sources that are configured to emit light that specifically facilitates release of nitric oxide from the one or more photolyzable nitric oxide donors.

60. The apparatus of claim 36, wherein the one or more light sources that are configured to emit light that facilitates release of nitric oxide from the one or more photolyzable nitric oxide donors comprise:

one or more light sources that are configured to emit light that is selected to avoid damage to one or more tissues.

61. The apparatus of claim 36, wherein the one or more light sources that are configured to emit light that facilitates release of nitric oxide from the one or more photolyzable nitric oxide donors comprise:

one or more status indicators.

62. The apparatus of claim 36, further comprising:

one or more photolyzable nitric oxide donors.

63. The apparatus of claim 62, wherein the one or more photolyzable nitric oxide donors comprise:

one or more photolyzable nitric oxide donors that include one or more diazeniumdiolates.

64. The apparatus of claim 62, wherein the one or more photolyzable nitric oxide donors comprise:

one or more photolyzable nitric oxide donors that are associated with one or more quantum dots.

65. The apparatus of claim 62, wherein the one or more photolyzable nitric oxide donors comprise:

one or more photolyzable nitric oxide donors that are associated with one or more fluorescent materials.

66. The apparatus of claim 62, wherein the one or more photolyzable nitric oxide donors comprise:

one or more photolyzable nitric oxide donors that are associated with one or more rare-earth materials that facilitate upconversion of energy.

67. The apparatus of claim 62, wherein the one or more photolyzable nitric oxide donors comprise:

one or more photolyzable nitric oxide donors that are coupled to one or more polymeric materials.

4-6. -6. (canceled)

9-10. -10. (canceled)

12-14. -14. (canceled)

20. (canceled)

23. (canceled)

26. (canceled)

34. (canceled)

37. (canceled)

44. (canceled)

46. (canceled)

48. (canceled)

55-58. -58. (canceled)

68. An apparatus comprising:

one or more photolyzable nitric oxide donors;

one or more light sources that are associated with one or more rare-earth materials and configured to emit light that is upconverted by the one or more rare-earth materials to facilitate release of nitric oxide from the one or more photolyzable nitric oxide donors; and

one or more substrates that are configured for operable association with the one or more light sources.

69. An apparatus comprising:

one or more photolyzable nitric oxide donors that are associated with one or more rare-earth materials;

one or more light sources that are configured to emit light that is upconverted by the one or more rare-earth materials to facilitate release of nitric oxide from the one or more photolyzable nitric oxide donors; and

one or more substrates that are configured for operable association with the one or more light sources.