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Rapid in vivo identification of biologically active nucleases

  • US 20090111119A1
  • Filed: 09/25/2008
  • Published: 04/30/2009
  • Est. Priority Date: 09/27/2007
  • Status: Active Grant
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1. A reporter construct for detecting double-stranded cleavage of a target sequence by one or more nucleases, the reporter construct comprising overlapping and non-functional sequences of a reporter gene separated by a target sequence recognized by the nuclease.

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